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MKNK2 and RPL7A
Number of citations of the paper that reports this interaction (PubMedID
20936779
)
36
Data Source:
BioGRID
(two hybrid)
MKNK2
RPL7A
Description
MAPK interacting serine/threonine kinase 2
ribosomal protein L7a
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Body
PML Body
Nucleus
Nucleolus
Cytoplasm
Cytosol
Ribosome
Focal Adhesion
Membrane
Cytosolic Large Ribosomal Subunit
Cytosolic Ribosome
Synapse
Ribonucleoprotein Complex
Molecular Function
Nucleotide Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Calcium/calmodulin-dependent Protein Kinase Activity
Protein Binding
Calmodulin Binding
ATP Binding
Calcium-dependent Protein Serine/threonine Kinase Activity
Kinase Activity
Transferase Activity
Metal Ion Binding
Protein Serine Kinase Activity
RNA Binding
Structural Constituent Of Ribosome
Protein Binding
Cadherin Binding
Biological Process
Regulation Of Translation
Protein Phosphorylation
Apoptotic Process
Cell Surface Receptor Signaling Pathway
Hemopoiesis
Intracellular Signal Transduction
Cellular Response To Arsenic-containing Substance
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Maturation Of LSU-rRNA
Cytoplasmic Translation
Translation
Ribosome Biogenesis
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Fostamatinib
Diseases
GWAS
Nonsyndromic cleft lip with or without cleft palate (
28087736
)
Malaria (
31844061
)
Interacting Genes
13 interacting genes:
CUL2
EIF4E
EIF4G1
ESR1
ESR2
MAPK1
MAPK14
MAPK8
MESD
PSMA1
RBX1
RPL7A
VBP1
9 interacting genes:
CCDC47
CTBP2
DUX4
MKNK2
POLR2M
SGO1
SOCS3
STAU1
USP7
Entrez ID
2872
6130
HPRD ID
05459
01712
Ensembl ID
ENSG00000099875
ENSG00000148303
Uniprot IDs
B3KS07
Q9HBH9
P62424
PDB IDs
2AC3
2AC5
2HW7
6CJ5
6CJE
6CJH
6CJW
6CJY
6CK3
6CK6
6CKI
6JLR
8P9B
8XFM
9HRC
4UG0
4V6X
5AJ0
5LKS
5T2C
6IP5
6IP6
6IP8
6LQM
6LSR
6LSS
6LU8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6W6L
6XA1
6Y0G
6Y2L
6Y57
6Y6X
6Z6L
6Z6M
6Z6N
6ZM7
6ZME
6ZMI
6ZMO
6ZVK
7A01
7BHP
7F5S
7OW7
7QVP
7XNX
7XNY
7ZJW
7ZJX
8A3D
8FKP
8FKQ
8FKR
8FKS
8FKT
8FKU
8FKV
8FKW
8FKX
8FKY
8FKZ
8FL2
8FL3
8FL4
8FL6
8FL7
8FL9
8FLA
8FLB
8FLC
8FLD
8FLE
8FLF
8G5Y
8G5Z
8G60
8G61
8G6J
8GLP
8IDT
8IDY
8IE3
8IFD
8IFE
8INE
8INF
8INK
8IPD
8IPX
8IPY
8IR1
8IR3
8JDJ
8JDK
8JDL
8JDM
8K2C
8OHD
8OJ0
8OJ5
8OJ8
8P2K
8QFD
8QOI
8QYX
8RL2
8UKB
8XSX
8XSY
8XSZ
8Y0W
8Y0X
8YOO
8YOP
9C3H
9G8M
9GMO
Enriched GO Terms of Interacting Partners
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MAP Kinase Activity
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Nuclear Estrogen Receptor Activity
Enzyme Binding
Cellular Response To Lipid
Response To Lipid
Cellular Response To Amino Acid Starvation
Response To Amino Acid Starvation
Response To Nutrient Levels
Cellular Response To Oxygen-containing Compound
MAPK Cascade
Energy Homeostasis
Cell Cycle G1/S Phase Transition
G1/S Transition Of Mitotic Cell Cycle
Cellular Response To Nutrient Levels
Estrogen Response Element Binding
Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway
Eukaryotic Translation Initiation Factor 4F Complex
Protein Metabolic Process
Post-transcriptional Regulation Of Gene Expression
Cullin-RING Ubiquitin Ligase Complex
Nucleus
Negative Regulation Of Autophagy
Mammary Gland Epithelial Cell Proliferation
Cul2-RING Ubiquitin Ligase Complex
Positive Regulation Of Cyclase Activity
Cytosol
Nuclear Steroid Receptor Activity
Peptidyl-threonine Phosphorylation
Intracellular Signal Transduction
Negative Regulation Of Catabolic Process
Regulation Of Autophagy
Estrogen Receptor Signaling Pathway
Negative Regulation Of Macromolecule Metabolic Process
P38MAPK Cascade
Mitotic Cell Cycle Phase Transition
Response To UV
Steroid Binding
Regulation Of Inflammatory Response
Cell Cycle Phase Transition
Negative Regulation Of Inflammatory Response To Antigenic Stimulus
Negative Regulation Of Metabolic Process
Canonical Inflammasome Complex Assembly
Behavioral Fear Response
Behavioral Defense Response
Cellular Response To Estradiol Stimulus
Cellular Response To Starvation
Regulation Of MRNA Stability
Macromolecule Metabolic Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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