KRT6C and KRT19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, cross-linking study)

		KRT6C	KRT19
Description		keratin 6C	keratin 19
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Cytosol Cytoskeleton Intermediate Filament Plasma Membrane Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Z Disc Sarcolemma Costamere Keratin Filament Extracellular Exosome Cell Periphery Terminal Web
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Muscle Structural Constituent Of Skin Epidermis Protein-containing Complex Binding
	Biological Process	Keratinization Intermediate Filament Cytoskeleton Organization Intermediate Filament Organization	Morphogenesis Of An Epithelium Notch Signaling Pathway Epithelial Cell Differentiation Response To Estrogen Intermediate Filament Organization Sarcomere Organization Cell Differentiation Involved In Embryonic Placenta Development
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin Developmental Lineage of Pancreatic Ductal Cells Developmental Lineage of Mammary Gland Luminal Epithelial Cells Developmental Lineage of Mammary Gland Alveolar Cells
Drugs
Diseases
GWAS
Interacting Genes		26 interacting genes: ACTN3 GOLGA2 KIFC3 KRT13 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 RNF26 SMARCB1 TFIP11 TRIM54	75 interacting genes: ABI2 AIRIM AMOT AMOTL2 ARL4A BEX2 CARD9 CCDC146 CCHCR1 CEP57L1 COPS4 DEPP1 DGCR6L DMD EIF4E2 EIF4ENIF1 ESR1 EXOC8 FAM107A FAM124B FANCG GFAP GLYCTK HAUS1 HGS IKZF3 KDM1A KIFC3 KRT1 KRT15 KRT4 KRT6A KRT6B KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT77 KRT78 KRT79 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LENG1 LGALS14 NFKBID PCDHB12 PCM1 PKN1 PLEKHA5 PNN POLL POLR1C PPP1R18 PSMA1 RCOR3 SFI1 SGF29 SMARCB1 SMARCE1 SNAPIN SPG21 TBC1D7 TCHP TFPT TUBG1 UBE2I UCHL5 USHBP1 ZNF638
Entrez ID		286887	3880
HPRD ID		17247	01007
Ensembl ID		ENSG00000170465	ENSG00000171345
Uniprot IDs		P48668	P08727
PDB IDs			8XTN 8XTO 8Y3S 8ZUG
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Structural Molecule Activity Epithelial Cell Differentiation Morphogenesis Of An Epithelium Tissue Morphogenesis Supramolecular Fiber Organization Cytoskeleton Organization Cytoskeleton Organelle Organization Anatomical Structure Morphogenesis Cell Differentiation Extracellular Exosome Cellular Developmental Process Developmental Process Hair Cycle Structural Constituent Of Cytoskeleton Epidermis Development Cytosol Hair Follicle Morphogenesis Hair Cycle Process Cell Periphery Tissue Development Z Disc Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Structural Constituent Of Muscle Protein Binding Intermediate Filament Cytoskeleton Regulation Of The Force Of Skeletal Muscle Contraction Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Spliceosomal Complex Disassembly Cornified Envelope	Intermediate Filament Organization Structural Constituent Of Skin Epidermis Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Keratin Filament Keratinization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Cytosol Protein Binding Structural Constituent Of Cytoskeleton Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Cytoskeleton Desmosome Epidermis Development Regulation Of Embryonic Development Regulation Of DNA Repair Cytoplasm
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