NSMCE2 and TSNAX

Number of citations of the paper that reports this interaction (PMID 16055714)
53

Data Source:
BioGRID (enzymatic study)

		NSMCE2	TSNAX
Gene Name		non-SMC element 2, MMS21 homolog (S. cerevisiae)	translin-associated factor X
Image
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus PML Body Smc5-Smc6 Complex	Nucleus Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Ligase Activity SUMO Transferase Activity	DNA Binding Single-stranded DNA Binding Endoribonuclease Activity Protein Transporter Activity Sequence-specific DNA Binding Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Telomere Maintenance Via Recombination Double-strand Break Repair Via Homologous Recombination Double-strand Break Repair Via Nonhomologous End Joining Mitotic Nuclear Division Protein Sumoylation Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion Positive Regulation Of Mitotic Metaphase/anaphase Transition Cell Division Cellular Senescence	Multicellular Organismal Development Spermatogenesis Gene Expression Protein Transport Cell Differentiation RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways			Regulatory RNA pathways Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS		Response to statin therapy ( 20339536)
Protein-Protein Interactions		4 interactors: ETV1 TSNAX TXLNA USP28	22 interactors: AIMP1 AKAP9 BLOC1S5 C1D CARD9 CDK5RAP2 CKAP4 GADD45G GOLGA3 KCNE4 KLC3 LDB2 LZTS2 MRFAP1L1 NSMCE2 PBXIP1 RALYL SUMO1 SUN1 TCF12 TSN TSNAXIP1
Entrez ID		286053	7257
HPRD ID		08131	04270
Ensembl ID		ENSG00000156831	ENSG00000116918
Uniprot IDs		Q96MF7	Q99598
PDB IDs		2YU4	3PJA 3QB5
Enriched GO Terms of Interacting Partners?			Protein Sumoylation Developmental Process Positive Regulation Of Cellular Metabolic Process Axon Cargo Transport Nuclear Envelope Organization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Multicellular Organismal Development Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion Cellular Localization Mitotic Cell Cycle Process
Tagcloud ?			bdi beadstation bipolar chinese disorder edition fourth genotyped genotyping goldengate guangzhou han haplotype haplotypes illumina lis1 lis1and machine manual meeting plink polymorphisms psychotic snp snps software statistic subgroups ten
Tagcloud (Difference) ?			bdi beadstation bipolar chinese disorder edition fourth genotyped genotyping goldengate guangzhou han haplotype haplotypes illumina lis1 lis1and machine manual meeting plink polymorphisms psychotic snp snps software statistic subgroups ten
Tagcloud (Intersection) ?