FAM153A and ROPN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM153A	ROPN1
Description		family with sequence similarity 153 member A	rhophilin associated tail protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Cilium Motile Cilium Cell Projection
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process		Flagellated Sperm Motility Cilium Organization Sperm Capacitation Protein Localization To Cilium
Pathways			RHO GTPases Activate Rhotekin and Rhophilins
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Benign childhood epilepsy with centro-temporal spikes ( 32580138) Household income ( 31844048) Household income (MTAG) ( 31844048)
Interacting Genes		3 interacting genes: DYNLL1 PLOD3 ROPN1	50 interacting genes: AKAIN1 AKAP14 AKAP3 AKAP5 AKAP7 AP1M1 BTBD16 CDC37 CEP57L1 CKS1B CNST DBF4B ERCC3 FAM110A FAM153A FAM153B FAM161A FAM90A1 GNL3L GPKOW HNRNPUL1 KIAA0753 KIF9 LENG1 LMO4 LNX1 LNX2 NTAQ1 PICK1 PKP2 POLR3C PRDM6 PRKAA1 PSMA1 RHPN1 RTP5 SDCBP SERTAD1 SORBS3 SPA17 SPG21 SYTL4 TRIM3 TSGA10IP TSHZ3 TSNAXIP1 TULP3 UBE2W VPS33A XKR3
Entrez ID		285596	54763
HPRD ID		14870	15269
Ensembl ID		ENSG00000170074	ENSG00000065371
Uniprot IDs		A0A087WYN1 A0A8V8TKN8 A0A8V8TM68 Q9UHL3	A0A140VKB2 Q9HAT0
PDB IDs
Enriched GO Terms of Interacting Partners?		Deoxyribonuclease Inhibitor Activity Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Regulation Of DNA Strand Resection Involved In Replication Fork Processing Nitric-oxide Synthase Inhibitor Activity Hydroxylysine Biosynthetic Process Basement Membrane Assembly Procollagen Galactosyltransferase Activity Procollagen Glucosyltransferase Activity Procollagen-lysine 5-dioxygenase Activity Cilium Organization Epidermis Morphogenesis Nitric-oxide Synthase Regulator Activity Peptidyl-lysine Hydroxylation Microtubule-based Movement Negative Regulation Of DNA-templated DNA Replication Negative Regulation Of Nitric Oxide Biosynthetic Process Intraciliary Retrograde Transport DNA Strand Resection Involved In Replication Fork Processing Endothelial Cell Morphogenesis Protein Hydroxylation Cilium L-ascorbic Acid Binding Sperm Capacitation Cytoplasmic Dynein Complex Small Molecule Binding Negative Regulation Of DNA Replication Lung Morphogenesis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus COP9 Signalosome Dynein Intermediate Chain Binding Substantia Nigra Development Developmental Process Involved In Reproduction Plasma Membrane Bounded Cell Projection Organization Motile Cilium Assembly Dynein Complex Microtubule Associated Complex Microtubule-based Process Aspartate Family Amino Acid Metabolic Process Rough Endoplasmic Reticulum Neural Tube Development Epithelial Cell Morphogenesis Basement Membrane Organization Extracellular Matrix Assembly Ciliary Tip Intraciliary Transport Enzyme Inhibitor Activity Ficolin-1-rich Granule Membrane Neural Nucleus Development Regulation Of Nitric Oxide Metabolic Process Axon Cytoplasm	Protein Kinase A Binding Protein Binding Protein Kinase A Regulatory Subunit Binding
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