EPHA10 and FHL3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EPHA10	FHL3
Gene Name		EPH receptor A10	four and a half LIM domains 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Stress Fiber Nucleus Focal Adhesion Z Disc
	Molecular Function	Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity Protein Binding ATP Binding	Actin Binding Zinc Ion Binding
	Biological Process	Axon Guidance Biological_process Peptidyl-tyrosine Phosphorylation Ephrin Receptor Signaling Pathway	Muscle Organ Development Actin Cytoskeleton Organization
Pathways		EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS		Prostate cancer (gene x gene interaction) ( 22219177)
Protein-Protein Interactions		4 interactors: BANP CAMK2D FHL3 TFCP2	88 interactors: A1CF ACTB ADAM15 ADAMTSL4 AIMP2 AMBP C14orf105 C9orf116 CDC25B CDC42EP1 CNNM3 CORO1A CSF1 CTBP2 DCDC2B E2F8 EFCAB12 EPHA10 EPM2AIP1 FAM154A FAM71C FAM90A1 FBXL18 FHL2 FHL5 FOSL2 GATA2 GCM2 HIPK1 HYAL2 ITGA7 KIRREL2 KLF3 KLF8 KRTAP12-1 KRTAP12-2 KTI12 LASP1 LMO2 LNX1 MAPK1 MED15 MPZL1 MRPL27 MYBPC1 MYBPHL MZF1 NPRL3 P4HA2 PAK7 PATL1 PHC2 PHF21A PLEKHF2 PPIG PTPN6 QRICH1 RAD21 RBM42 RFX3 RFX6 RHEBL1 RNMTL1 SAP30BP SLAIN1 SLC25A46 SLC44A3 SMAD2 SMAD3 SMAD4 SNRPG SREBF2 SRF TMX3 TRAF3IP2 TRIM27 TRIP6 TRO TTLL10 TYK2 TYMSOS UBE2I UBE2Q1 WNK1 YPEL3 ZNF417 ZNF512B ZNRD1
Entrez ID		284656	2275
HPRD ID		08163	09101
Ensembl ID		ENSG00000183317	ENSG00000183386
Uniprot IDs		Q4G0R4 Q5JZY3 Q8N289	Q13643 Q96C98
PDB IDs			1WYH 2CUQ 2EHE
Enriched GO Terms of Interacting Partners?		Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cardiac Muscle Cell Contraction Regulation Of Generation Of L-type Calcium Current Regulation Of Histone Deacetylase Activity Positive Regulation Of Rac Protein Signal Transduction Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Relaxation Of Cardiac Muscle Negative Regulation Of Sodium Ion Transmembrane Transport Regulation Of Cardiac Muscle Cell Action Potential Cellular Potassium Ion Homeostasis Regulation Of Relaxation Of Muscle Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Sodium Ion Transport Regulation Of Cell Communication By Electrical Coupling Relaxation Of Cardiac Muscle Potassium Ion Homeostasis Muscle Structure Development Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Cardiac Muscle Hypertrophy Relaxation Of Muscle Regulation Of Heart Rate By Cardiac Conduction Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Actin Filament-based Process Cardiac Muscle Hypertrophy Positive Regulation Of Smooth Muscle Cell Migration Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Muscle Hypertrophy Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Cardiac Muscle Hypertrophy Regulation Of Cellular Response To Heat Regulation Of The Force Of Heart Contraction Cardiac Muscle Tissue Growth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Histone Deacetylation Regulation Of Membrane Depolarization Regulation Of Sodium Ion Transmembrane Transport Regulation Of Rac Protein Signal Transduction Negative Regulation Of Transporter Activity Regulation Of Smooth Muscle Cell Migration Actin-mediated Cell Contraction Regulation Of Cardiac Muscle Cell Contraction Regulation Of G2/M Transition Of Mitotic Cell Cycle Cardiac Conduction Peptidyl-threonine Phosphorylation Regulation Of Cell Cycle G2/M Phase Transition Negative Regulation Of Ion Transmembrane Transport Cellular Response To Calcium Ion Regulation Of Protein Deacetylation	RNA Metabolic Process Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process SMAD Protein Complex Assembly Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Cellular Process Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Cell Proliferation Negative Regulation Of RNA Biosynthetic Process Tissue Development Positive Regulation Of Cellular Metabolic Process Cell Death Death Multicellular Organismal Homeostasis Positive Regulation Of Epithelial To Mesenchymal Transition Endoderm Development Negative Regulation Of Cell Growth Embryonic Organ Development Positive Regulation Of Metabolic Process Primary MiRNA Processing Organ Development Apoptotic Process
Tagcloud ?			accompanied adhesion anchorage antiproliferative arrest b1 cip1 downregulated g1 g2 half implicated interfering knockdown lim marked marker member mobility p21 progression regulator sirna suppressed thereby transduction unclear waf1
Tagcloud (Difference) ?			accompanied adhesion anchorage antiproliferative arrest b1 cip1 downregulated g1 g2 half implicated interfering knockdown lim marked marker member mobility p21 progression regulator sirna suppressed thereby transduction unclear waf1
Tagcloud (Intersection) ?