GPR22 and CEBPE

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GPR22	CEBPE
Gene Name		G protein-coupled receptor 22	CCAAT/enhancer binding protein (C/EBP), epsilon
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane	Nucleoplasm
	Molecular Function	G-protein Coupled Receptor Activity Peptide Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	G-protein Coupled Receptor Signaling Pathway Cellular Response To Hormone Stimulus Response To Peptide	Transcription, DNA-templated Phagocytosis Defense Response Macrophage Differentiation Cytokine Biosynthetic Process Defense Response To Bacterium Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Lipopolysaccharide
Pathways
Drugs
Diseases
GWAS			Acute lymphoblastic leukemia (childhood) ( 23512250 19684604)
Protein-Protein Interactions		3 interactors: CEBPE NFATC4 TFAP2C	44 interactors: ALX4 ATF3 ATF4 ATF5 BATF BATF2 BATF3 CCT7 CEBPA CEBPD CEBPG COPS3 CSNK1A1L DDIT3 DENND4A E2F1 EDA2R FOS FOSL1 GATA1 GPR22 GTF2A1L IL7 JUN KDM2B LDOC1 MED16 MLLT6 MYB NELFB PIAS1 POU2F1 PSAT1 RB1 SIPA1L1 SPI1 STAT6 TAF5L TBX2 TCEB2 UBE2I ZFP2 ZMYM2 ZNF384
Entrez ID		2845	1053
HPRD ID		03552	02852
Ensembl ID		ENSG00000172209	ENSG00000092067
Uniprot IDs		A4D0R8 B3KV13 Q3KNS9 Q99680	Q15744
PDB IDs			3T92
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Branching Morphogenesis Of An Epithelial Tube Dichotomous Subdivision Of Terminal Units Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Morphogenesis Of A Branching Epithelium Positive Regulation Of Cellular Biosynthetic Process Morphogenesis Of A Branching Structure Regulation Of Transcription From RNA Polymerase II Promoter Epithelial Tube Morphogenesis Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Germ-line Stem Cell Maintenance Branch Elongation Involved In Mammary Gland Duct Branching Transcription, DNA-templated Tube Morphogenesis RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Keratinocyte Development Morphogenesis Of An Epithelium Sebaceous Gland Development Cellular Response To Lithium Ion Organ Development Tissue Morphogenesis Forebrain Neuron Fate Commitment Macrophage Differentiation RNA Metabolic Process Tube Development Mammary Gland Epithelial Cell Proliferation Cytokine Biosynthetic Process Cell Differentiation Positive Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Trophectodermal Cell Differentiation Branch Elongation Of An Epithelium Cellular Macromolecule Biosynthetic Process Response To Lithium Ion Cytokine Metabolic Process Macromolecule Biosynthetic Process Axis Elongation Blastocyst Formation System Development Anatomical Structure Formation Involved In Morphogenesis Patterning Of Blood Vessels Regulation Of Transcription, DNA-templated Epithelium Development Negative Regulation Of Transcription, DNA-templated Branching Involved In Mammary Gland Duct Morphogenesis	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Gene Expression Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Leukocyte Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Cellular Process Myeloid Cell Differentiation Hemopoiesis Myeloid Leukocyte Differentiation Cellular Metabolic Process Immune System Development Negative Regulation Of Cellular Metabolic Process Organ Development Dendritic Cell Differentiation Anatomical Structure Development Regulation Of Sequence-specific DNA Binding Transcription Factor Activity System Development Myeloid Dendritic Cell Differentiation Leukocyte Activation Myeloid Dendritic Cell Activation
Tagcloud ?		asymmetry cilia ciliogenesis details foxj1a gpcr gpcrs knock kupffer kv lefty1 lefty2 looping lpm lr master mesodermal morpholino organelles orphan patterning pitx2a player protrude randomization rfx2 southpaw tem vesicle	10months 12p absolutely aligned alive altogether apart arid5b associating bcp boy chance divergent etv6 girl gstm1 gstt1 haa ikzf1 leukocytosis microsatellite nqo1 predisposition ptprj relapsed runx1 sibs tp63 twinned
Tagcloud (Difference) ?		asymmetry cilia ciliogenesis details foxj1a gpcr gpcrs knock kupffer kv lefty1 lefty2 looping lpm lr master mesodermal morpholino organelles orphan patterning pitx2a player protrude randomization rfx2 southpaw tem vesicle	10months 12p absolutely aligned alive altogether apart arid5b associating bcp boy chance divergent etv6 girl gstm1 gstt1 haa ikzf1 leukocytosis microsatellite nqo1 predisposition ptprj relapsed runx1 sibs tp63 twinned
Tagcloud (Intersection) ?