WDR62 and RALY

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		WDR62	RALY
Gene Name		WD repeat domain 62	RALY heterogeneous nuclear ribonucleoprotein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Cytoplasm	Nucleus Catalytic Step 2 Spliceosome
	Molecular Function		Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Cerebral Cortex Development Neurogenesis	MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS			Breast cancer ( 22976474)
Protein-Protein Interactions		9 interactors: DYRK2 LRIF1 MAGEB4 MAPK8 MAPK9 P4HA3 RALY TBC1D23 TBP	11 interactors: CELF1 HNRNPC HNRNPD HNRNPH1 HNRNPK KHDRBS1 PCBP1 PIK3CD QKI SPG7 WDR62
Entrez ID		284403	22913
HPRD ID		10721	11480
Ensembl ID		ENSG00000075702	ENSG00000125970
Uniprot IDs		O43379	Q53GL6 Q9UKM9
PDB IDs			1WF1
Enriched GO Terms of Interacting Partners?		JUN Phosphorylation Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Response To Cadmium Ion Apoptotic Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway JNK Cascade Regulation Of Circadian Rhythm Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Response To UV Activation Of Innate Immune Response Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Positive Regulation Of Innate Immune Response Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Deacetylase Activity Positive Regulation Of Prostaglandin Biosynthetic Process Response To Mechanical Stimulus Positive Regulation Of Metabolic Process MAPK Cascade Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Determination Of Dorsal Identity Regulation Of Innate Immune Response Peptidyl-amino Acid Modification Negative Regulation Of NFAT Protein Import Into Nucleus Apoptotic Process Fc Receptor Signaling Pathway Programmed Cell Death Signal Transduction By Phosphorylation Positive Regulation Of Hydrolase Activity Cell Death Death Cellular Response To Nitric Oxide Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Prostaglandin Secretion Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process	MRNA Processing MRNA Metabolic Process RNA Processing RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Posttranscriptional Regulation Of Gene Expression Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Translation RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Translation Nitrogen Compound Metabolic Process Positive Regulation Of RNA Export From Nucleus Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter 3'-UTR-mediated MRNA Destabilization Regulation Of RNA Splicing Mast Cell Differentiation Natural Killer Cell Chemotaxis B Cell Chemotaxis Spermatid Development Neutrophil Extravasation Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Mast Cell Chemotaxis Regulation Of Protein Metabolic Process Spermatid Differentiation Respiratory Burst Involved In Defense Response Regulation Of Gene Expression Circadian Regulation Of Translation MRNA Destabilization Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Gene Expression T Cell Chemotaxis Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Receptor Biosynthetic Process 3'-UTR-mediated MRNA Stabilization RNA Destabilization Germ Cell Development Respiratory Burst Regulation Of RNA Export From Nucleus Positive Regulation Of Translational Initiation Long-chain Fatty Acid Biosynthetic Process RNA Interference Regulation Of Receptor Biosynthetic Process Lymphocyte Chemotaxis
Tagcloud ?		arrested aspm autosomal centrosomal defect disappear dramatic encode fourth ideal knocking lapse mcph microcephaly mitosis mitotic mitotically morpholino neuroepithelium odf2 pole prometaphase recessive rescue retardation retinas saw spindle stil	asip avian birds buds chickens color document dorsoventral eif2b encompasses feather hair implying lethal mammals melanin patterning pigmentation places quail quails remarkable similarities skins slc24a5 universal ventral vertebrates yellow
Tagcloud (Difference) ?		arrested aspm autosomal centrosomal defect disappear dramatic encode fourth ideal knocking lapse mcph microcephaly mitosis mitotic mitotically morpholino neuroepithelium odf2 pole prometaphase recessive rescue retardation retinas saw spindle stil	asip avian birds buds chickens color document dorsoventral eif2b encompasses feather hair implying lethal mammals melanin patterning pigmentation places quail quails remarkable similarities skins slc24a5 universal ventral vertebrates yellow
Tagcloud (Intersection) ?