ENDOV and NELFCD

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		ENDOV	NELFCD
Gene Name		endonuclease V	negative elongation factor complex member C/D
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm	Nucleoplasm Membrane NELF Complex
	Molecular Function	Magnesium Ion Binding Single-stranded RNA Binding Endodeoxyribonuclease Activity, Producing 5'-phosphomonoesters Endoribonuclease Activity, Producing 5'-phosphomonoesters Structure-specific DNA Binding	Protein Binding
	Biological Process	DNA Catabolic Process, Endonucleolytic DNA Repair RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Transcription
Pathways			Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat HIV Infection Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: NELFCD PRPSAP2	19 interactors: AAMP AR ARAF ARPC4 CACNA1A DNAJA1 ENDOV EPRS FRMD5 GSTM4 HDAC11 MTA1 NELFA PRMT5 SERF2 SMAD4 TXK UBE3A ZNF638
Entrez ID		284131	51497
HPRD ID		08758	16096
Ensembl ID		ENSG00000173818	ENSG00000101158
Uniprot IDs		Q8N8Q3	H0UI80 Q8IXH7
PDB IDs
Enriched GO Terms of Interacting Partners?			Androgen Receptor Signaling Pathway Endothelial Cell Activation Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process RNA Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process RNA Biosynthetic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Intracellular Receptor Signaling Pathway Growth Regulation Of Protein Ubiquitination Gene Expression Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Death Cellular Macromolecule Biosynthetic Process Negative Regulation Of Integrin Biosynthetic Process Cerebellar Molecular Layer Development Sperm Entry Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Regulation Of Metabolic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Stimulus Cellular Metabolic Process Prostate Gland Development Heterocycle Metabolic Process Biosynthetic Process Prolyl-tRNA Aminoacylation Vestibular Nucleus Development Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Nephrogenic Mesenchyme Morphogenesis Positive Regulation Of Protein Autoubiquitination Regulation Of Establishment Of Protein Localization Rhythmic Process Circadian Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Glutamyl-tRNA Aminoacylation Positive Regulation Of Integrin Biosynthetic Process Cerebellum Maturation Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis Musculoskeletal Movement, Spinal Reflex Action Regulation Of Protein Autoubiquitination NK T Cell Differentiation Positive Regulation Of Cellular Metabolic Process Cellular Component Assembly
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