KCTD21 and CRLF3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KCTD21	CRLF3
Description		potassium channel tetramerization domain containing 21	cytokine receptor like factor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding Identical Protein Binding Histone Deacetylase Binding Cullin Family Protein Binding	DNA Binding Protein Binding Identical Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Negative Regulation Of Smoothened Signaling Pathway Protein Homooligomerization	Negative Regulation Of Cell Growth Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Tourette syndrome ( 30818990)	Birth weight ( 27680694) Chronic obstructive pulmonary disease ( 30804561) Cutaneous leishmaniasis ( 32830257) Height ( 18391951 28552196) Hip circumference adjusted for BMI ( 34021172) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 29403010) Platelet distribution width ( 32888494) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		10 interacting genes: C22orf15 CRLF3 KCTD15 LONRF1 NMRK1 NTAQ1 PPL RNF25 UFM1 ZMYND19	10 interacting genes: APPL2 DDIT4L KCTD21 KDM1A L3MBTL3 LGALS14 MYOZ3 RBM14 VPS25 ZFP1
Entrez ID		283219	51379
HPRD ID		18763	16757
Ensembl ID		ENSG00000188997	ENSG00000176390
Uniprot IDs		Q4G0X4	Q8IUI8
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Regulation Of Chromatin Organization
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