GPM6A and PAM16

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		GPM6A	PAM16
Description		glycoprotein M6A	presequence translocase associated motor 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Filopodium Axon Growth Cone Cell Projection Neuron Projection Neuronal Cell Body Dendritic Spine Axonal Growth Cone Synapse Presynaptic Active Zone Membrane Extracellular Exosome Parallel Fiber To Purkinje Cell Synapse Presynapse Glutamatergic Synapse Extracellular Vesicle	PAM Complex, Tim23 Associated Import Motor Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Mitochondrial Matrix Membrane Protein-containing Complex Matrix Side Of Mitochondrial Inner Membrane
	Molecular Function	Calcium Channel Activity Protein Binding	Protein Binding
	Biological Process	Neuron Migration Neural Retina Development Nervous System Development Synapse Assembly Response To Bacterium Neuron Projection Development Neuron Projection Morphogenesis Stem Cell Differentiation Regulation Of Synapse Organization Positive Regulation Of Filopodium Assembly Calcium Ion Transmembrane Transport	Ossification Intracellular Protein Transport Protein Transport Protein Import Into Mitochondrial Matrix Negative Regulation Of ATP-dependent Activity
Pathways			Mitochondrial protein import
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) Educational attainment ( 23722424) Household income (MTAG) ( 31844048) Major depressive disorder x sex interaction ( 34099189) Mortality in heart failure ( 20400778) Schizophrenia ( 25056061 28991256 29483656 30285260) Sensorimotor dexterity ( 31596458) Sepsis (28-day mortality) ( 32592749) Temperament (bipolar disorder) ( 22365631)	Erectile dysfunction ( 30583798) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		2 interacting genes: PAM16 PRKCA	9 interacting genes: ARL6IP1 BLOC1S2 CEP70 DNMT3B FEZ1 GPM6A MEOX2 MRFAP1 PGRMC1
Entrez ID		2823	51025
HPRD ID		03174	14798
Ensembl ID		ENSG00000150625	ENSG00000217930
Uniprot IDs		P51674	Q9Y3D7
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of ATP-dependent Activity Response To Estradiol Anterior Neural Tube Closure Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Cellular Response To Staurosporine Response To Reactive Oxygen Species Phospholipase A2 Activator Activity Response To Glucocorticoid Response To Corticosteroid Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Angiotensin-activated Signaling Pathway Histone H3T6 Kinase Activity Alphav-beta3 Integrin-PKCalpha Complex Protein Kinase C Signaling Luteolysis Glial Cell Apoptotic Process Regulation Of Angiotensin-activated Signaling Pathway PAM Complex, Tim23 Associated Import Motor Response To Anesthetic Catabolic Process Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Matrix Side Of Mitochondrial Inner Membrane	Gamma-tubulin Binding Plasma Membrane Bounded Cell Projection Organization Neuron Projection Development Cell Projection Organization DNA (cytosine-5-)-methyltransferase Activity, Acting On CpG Substrates Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Neuronal Cell Body
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