GPM6A and PAM16

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		GPM6A	PAM16
Gene Name		glycoprotein M6A	presequence translocase-associated motor 16 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Filopodium Vesicle Neuron Projection Neuronal Cell Body Dendritic Spine Axonal Growth Cone Extracellular Vesicular Exosome	Presequence Translocase-associated Import Motor Mitochondrial Inner Membrane Presequence Translocase Complex Mitochondrial Matrix Extrinsic Component Of Mitochondrial Inner Membrane Protein Complex
	Molecular Function	Calcium Channel Activity Protein Binding	Protein Binding
	Biological Process	Neuron Migration Neural Retina Development Synapse Assembly Neuron Projection Morphogenesis Stem Cell Differentiation Positive Regulation Of Filopodium Assembly Calcium Ion Transmembrane Transport	Protein Targeting To Mitochondrion Protein Import Into Mitochondrial Matrix Negative Regulation Of ATPase Activity Cellular Protein Metabolic Process
Pathways			Mitochondrial protein import
Drugs
Diseases
GWAS		Educational attainment ( 23722424) Mortality among heart failure patients ( 20400778) Temperament (bipolar disorder) ( 22365631)
Protein-Protein Interactions		2 interactors: PAM16 PRKCA	9 interactors: ARL6IP1 BLOC1S2 CEP70 DNAJC19 DNMT3B FEZ1 GPM6A MRFAP1 PGRMC1
Entrez ID		2823	51025
HPRD ID		03174	14798
Ensembl ID		ENSG00000150625	ENSG00000217930
Uniprot IDs		P51674	I3L3T0 Q9Y3D7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Dense Core Granule Biogenesis Histone H3-T6 Phosphorylation Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Protein Import Into Mitochondrial Matrix Negative Regulation Of ATPase Activity Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Negative Regulation Of Glucose Import Positive Regulation Of Macrophage Differentiation Desmosome Organization Negative Regulation Of Catalytic Activity Regulation Of Platelet Aggregation Negative Regulation Of Glucose Transport Induction Of Positive Chemotaxis Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Regulation Of Rhodopsin Mediated Signaling Pathway Negative Regulation Of CAMP Biosynthetic Process Activation Of Adenylate Cyclase Activity Regulation Of Cardiac Muscle Hypertrophy Rhodopsin Mediated Signaling Pathway Regulation Of Platelet Activation Positive Regulation Of Positive Chemotaxis Negative Regulation Of CAMP Metabolic Process Regulation Of The Force Of Heart Contraction Inactivation Of MAPK Activity Mitotic Nuclear Envelope Disassembly Positive Regulation Of Adenylate Cyclase Activity Negative Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Nucleotide Metabolic Process Histone Phosphorylation Regulation Of ATPase Activity Nuclear Envelope Disassembly Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Lyase Activity Peptidyl-threonine Phosphorylation Intracellular Protein Transmembrane Transport Activation Of Phospholipase C Activity Neutrophil Chemotaxis Positive Regulation Of Myeloid Leukocyte Differentiation Neutrophil Migration Regulation Of Adenylate Cyclase Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of Endothelial Cell Migration Protein Transmembrane Transport Granulocyte Chemotaxis	Generation Of Neurons Neurogenesis Neuron Projection Development Neuron Development Neuron Differentiation Cell Projection Organization Nervous System Development System Development Movement Of Cell Or Subcellular Component Neuron Projection Morphogenesis S-adenosylmethioninamine Metabolic Process Mitochondrial Transport Multicellular Organismal Development DNA Methylation On Cytosine Within A CG Sequence Anatomical Structure Development Cell Development C-5 Methylation Of Cytosine S-adenosylhomocysteine Metabolic Process Cell Projection Morphogenesis Cell Differentiation Cell Part Morphogenesis Methylation-dependent Chromatin Silencing Establishment Of Localization In Cell Developmental Process Mitochondrial Outer Membrane Permeabilization Platelet Dense Granule Organization Positive Regulation Of Cell Projection Organization Cell Morphogenesis Negative Regulation Of Histone H3-K9 Methylation DNA Methylation On Cytosine Negative Regulation Of Macroautophagy Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Establishment Of Organelle Localization Positive Regulation Of Neuron Differentiation Cellular Localization Positive Regulation Of Histone H3-K4 Methylation Establishment Of Mitochondrion Localization Protein Complex Localization Negative Regulation Of Histone Methylation Positive Regulation Of Mitochondrial Membrane Permeability Locomotion Axon Guidance Anterograde Synaptic Vesicle Transport Mitochondrion Organization Melanosome Organization Microtubule Nucleation Pigment Granule Organization Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Neurogenesis Regulation Of Histone H3-K4 Methylation
Tagcloud ?		3t3 alters anchorage arntl2 bfsp2 bmp7 celsr1 confocal deregulated etv5 exhibits fbln1 filopodia fmn2 gfra2 gpm6b graffi homologs malignancies mulv nih nln oligonucleotide oncogenes parm peri protrusions punctate semi
Tagcloud (Difference) ?		3t3 alters anchorage arntl2 bfsp2 bmp7 celsr1 confocal deregulated etv5 exhibits fbln1 filopodia fmn2 gfra2 gpm6b graffi homologs malignancies mulv nih nln oligonucleotide oncogenes parm peri protrusions punctate semi
Tagcloud (Intersection) ?