SULT1B1 and SULT2B1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SULT1B1	SULT2B1
Gene Name		sulfotransferase family, cytosolic, 1B, member 1	sulfotransferase family, cytosolic, 2B, member 1
Image
Gene Ontology Annotations	Cellular Component	Cytosol	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Aryl Sulfotransferase Activity Sulfotransferase Activity	Alcohol Sulfotransferase Activity Protein Binding Steroid Sulfotransferase Activity
	Biological Process	Cellular Biogenic Amine Metabolic Process Xenobiotic Metabolic Process Steroid Metabolic Process Flavonoid Metabolic Process Phenol-containing Compound Metabolic Process Epithelial Cell Differentiation Thyroid Hormone Metabolic Process Small Molecule Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation	Sulfate Assimilation Xenobiotic Metabolic Process Steroid Metabolic Process Small Molecule Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective UGT1A4 causes hyperbilirubinemia Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Cytosolic sulfonation of small molecules Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GGT1 causes Glutathionuria (GLUTH) Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs			Dehydroepiandrosterone Adenosine-3\'-5\'-Diphosphate Pregnenolone N-Cyclohexyltaurine
Diseases
GWAS
Protein-Protein Interactions		4 interactors: POT1 SDCBP SULT2A1 SULT2B1	6 interactors: ACYP2 ALS2CR12 PRICKLE3 SULT1A1 SULT1B1 SULT1E1
Entrez ID		27284	6820
HPRD ID		07088	04991
Ensembl ID			ENSG00000088002
Uniprot IDs		O43704	O00204
PDB IDs		2Z5F 3CKL	1Q1Q 1Q1Z 1Q20 1Q22
Enriched GO Terms of Interacting Partners?		3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Positive Regulation Of DNA Strand Elongation Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Response To Xenobiotic Stimulus Sulfate Assimilation Telomere Formation Via Telomerase Bile Acid Catabolic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly Purine Nucleoside Metabolic Process Steroid Metabolic Process Positive Regulation Of Helicase Activity Regulation Of Extracellular Vesicular Exosome Assembly Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Ribonucleotide Metabolic Process Nucleoside Metabolic Process Purine Nucleotide Metabolic Process Positive Regulation Of Telomerase Activity Telomere Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Ribose Phosphate Metabolic Process Sulfur Compound Metabolic Process Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Positive Regulation Of Organelle Organization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Substrate-dependent Cell Migration, Cell Extension Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Nucleotide Metabolic Process Positive Regulation Of DNA Biosynthetic Process Sulfation RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Steroid Catabolic Process Positive Regulation Of Organelle Assembly Nucleobase-containing Small Molecule Metabolic Process Telomere Maintenance Via Telomere Lengthening Substrate-dependent Cell Migration Bile Acid Metabolic Process Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of Organelle Organization Positive Regulation Of Exocytosis Organophosphate Metabolic Process	3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Response To Xenobiotic Stimulus Hormone Metabolic Process Flavonoid Metabolic Process Estrogen Metabolic Process Purine Nucleoside Metabolic Process Steroid Metabolic Process Regulation Of Hormone Levels Ribonucleotide Metabolic Process Nucleoside Metabolic Process Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Sulfur Compound Metabolic Process Phenol-containing Compound Metabolic Process Nucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Amine Metabolic Process Organophosphate Metabolic Process Organic Acid Metabolic Process Phosphate-containing Compound Metabolic Process Lipid Metabolic Process Thyroid Hormone Metabolic Process Catecholamine Metabolic Process Small Molecule Metabolic Process Cellular Biogenic Amine Metabolic Process
Tagcloud ?		17p 20q 8p 8q aberration abhd12 abhd2 affymetrix arhgdib cna copy crc cxcl6 deployed integrating loc440995 oit3 omics organizing rab12 ralbp1 rnmt s1000a2 s100a2 sty tokyo tyms ugt2b28 written	1a akr1c3 androgenic androstenedione comt cyp19a1 cyp1b1 cyp3a5 e1s ers esr2 estrogens extents gper gstp1 hec hieec hsd17b1 hsd17b12 hsd17b7 hsd3b2 hydroxyestrogens ishikawa metabolized nqo2 quinones sulfatase ugt2b7
Tagcloud (Difference) ?		17p 20q 8p 8q aberration abhd12 abhd2 affymetrix arhgdib cna copy crc cxcl6 deployed integrating loc440995 oit3 omics organizing rab12 ralbp1 rnmt s1000a2 s100a2 sty tokyo tyms ugt2b28 written	1a akr1c3 androgenic androstenedione comt cyp19a1 cyp1b1 cyp3a5 e1s ers esr2 estrogens extents gper gstp1 hec hieec hsd17b1 hsd17b12 hsd17b7 hsd3b2 hydroxyestrogens ishikawa metabolized nqo2 quinones sulfatase ugt2b7
Tagcloud (Intersection) ?