SULT1B1 and SULT2B1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)

		SULT1B1	SULT2B1
Description		sulfotransferase family 1B member 1	sulfotransferase family 2B member 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Extracellular Exosome
	Molecular Function	Aryl Sulfotransferase Activity Protein Binding Sulfotransferase Activity Transferase Activity	Nucleic Acid Binding Alcohol Sulfotransferase Activity Protein Binding Sulfotransferase Activity Cholesterol Binding Transferase Activity Small Molecule Binding Steroid Sulfotransferase Activity Cholesterol Sulfotransferase Activity Steroid Hormone Binding
	Biological Process	Ethanol Catabolic Process Biogenic Amine Metabolic Process Xenobiotic Metabolic Process Flavonoid Metabolic Process Phenol-containing Compound Metabolic Process Epithelial Cell Differentiation Thyroid Hormone Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation	Lipid Metabolic Process Steroid Metabolic Process Cholesterol Metabolic Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of Epidermal Cell Differentiation 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation
Pathways		Cytosolic sulfonation of small molecules
Drugs		Adenosine 3',5'-diphosphate	Adenosine 3',5'-diphosphate Pregnenolone N-cyclohexyltaurine
Diseases
GWAS		Nicotine dependence ( 28440896) Uterine fibroids ( 30194396 31649266) White matter hyperintensity volume ( 33293549)	Elevated serum carcinoembryonic antigen levels ( 24941225) Non-oily fish consumption ( 32066663) Resting metabolic rate ( 28476931)
Interacting Genes		4 interacting genes: POT1 SDCBP SULT2A1 SULT2B1	12 interacting genes: ACYP2 DDIT4L FLACC1 KLHL8 PRICKLE3 REL SRP72 SULT1A1 SULT1B1 SULT1C3 SULT1E1 ZNF497
Entrez ID		27284	6820
HPRD ID		07088	04991
Ensembl ID		ENSG00000173597	ENSG00000088002
Uniprot IDs		O43704	O00204
PDB IDs		2Z5F 3CKL	1Q1Q 1Q1Z 1Q20 1Q22
Enriched GO Terms of Interacting Partners?		Alcohol Sulfotransferase Activity Steroid Sulfotransferase Activity 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation Sulfotransferase Activity Interleukin-5 Receptor Complex Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Cholesterol Metabolic Process Sterol Metabolic Process Interleukin-5 Receptor Binding Cholesterol Sulfotransferase Activity Bile Acid Catabolic Process Bile-salt Sulfotransferase Activity Positive Regulation Of Telomeric Loop Disassembly 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding Telomeric D-loop Binding Telomere Assembly Steroid Metabolic Process Sulfur Compound Metabolic Process Single-stranded Telomeric DNA Binding Regulation Of Extracellular Exosome Assembly Steroid Hormone Binding Shelterin Complex Purine Ribonucleotide Metabolic Process Alcohol Metabolic Process Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process DEAD/H-box RNA Helicase Binding Nuclear Telomere Cap Complex Telomeric D-loop Disassembly Substrate-dependent Cell Migration, Cell Extension 3'-phosphoadenosine 5'-phosphosulfate Binding G-rich Strand Telomeric DNA Binding Purine Nucleotide Metabolic Process Telomeric Loop Disassembly Ethanol Catabolic Process Telomere Capping Ethanol Metabolic Process Nucleotide Metabolic Process Positive Regulation Of Exosomal Secretion Negative Regulation Of Receptor Internalization Regulation Of DNA Strand Elongation Regulation Of Exosomal Secretion	Aryl Sulfotransferase Activity 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation Sulfotransferase Activity Ethanol Catabolic Process Ethanol Metabolic Process Flavonol 3-sulfotransferase Activity Alcohol Catabolic Process Steroid Sulfotransferase Activity Sulfur Compound Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Binding Flavonoid Metabolic Process Purine Ribonucleotide Metabolic Process Alcohol Metabolic Process Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process Xenobiotic Metabolic Process Purine Nucleotide Metabolic Process Thyroid Hormone Metabolic Process Nucleotide Metabolic Process Estrogen Metabolic Process Purine-containing Compound Metabolic Process Hormone Metabolic Process Nucleoside Phosphate Metabolic Process Steroid Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Estrogen Catabolic Process Estrone Sulfotransferase Activity Biogenic Amine Metabolic Process Acylphosphatase Activity Organic Acid Metabolic Process Amine Metabolic Process Bile-salt Sulfotransferase Activity Phosphate-containing Compound Metabolic Process Carbohydrate Derivative Metabolic Process Phenol-containing Compound Metabolic Process Alcohol Sulfotransferase Activity NF-kappaB Complex Organophosphate Metabolic Process Cytoplasm Signal Recognition Particle 7S RNA Binding Outer Dense Fiber Signal Recognition Particle Binding Signal Recognition Particle, Endoplasmic Reticulum Targeting TPR Domain Binding Regulation Of Hormone Levels Modified Amino Acid Metabolic Process Dopamine Catabolic Process Catecholamine Catabolic Process
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