SULT1B1

Gene Name		sulfotransferase family, cytosolic, 1B, member 1
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Gene Ontology Annotations	Cellular Component	Cytosol
	Molecular Function	Aryl Sulfotransferase Activity Sulfotransferase Activity
	Biological Process	Cellular Biogenic Amine Metabolic Process Xenobiotic Metabolic Process Steroid Metabolic Process Flavonoid Metabolic Process Phenol-containing Compound Metabolic Process Epithelial Cell Differentiation Thyroid Hormone Metabolic Process Small Molecule Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective UGT1A4 causes hyperbilirubinemia Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Cytosolic sulfonation of small molecules Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GGT1 causes Glutathionuria (GLUTH) Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: POT1 SDCBP SULT2A1 SULT2B1
Entrez ID		27284
HPRD ID		07088
Ensembl ID
Uniprot IDs		O43704
PDB IDs		2Z5F 3CKL
Enriched GO Terms of Interacting Partners?		3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Positive Regulation Of DNA Strand Elongation Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Response To Xenobiotic Stimulus Sulfate Assimilation Telomere Formation Via Telomerase Bile Acid Catabolic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly Purine Nucleoside Metabolic Process Steroid Metabolic Process Positive Regulation Of Helicase Activity Regulation Of Extracellular Vesicular Exosome Assembly Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Ribonucleotide Metabolic Process Nucleoside Metabolic Process Purine Nucleotide Metabolic Process Positive Regulation Of Telomerase Activity Telomere Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Ribose Phosphate Metabolic Process Sulfur Compound Metabolic Process Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Positive Regulation Of Organelle Organization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Substrate-dependent Cell Migration, Cell Extension Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Nucleotide Metabolic Process Positive Regulation Of DNA Biosynthetic Process Sulfation RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Steroid Catabolic Process Positive Regulation Of Organelle Assembly Nucleobase-containing Small Molecule Metabolic Process Telomere Maintenance Via Telomere Lengthening Substrate-dependent Cell Migration Bile Acid Metabolic Process Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of Organelle Organization Positive Regulation Of Exocytosis Organophosphate Metabolic Process
Tagcloud ?		17p 20q 8p 8q aberration abhd12 abhd2 affymetrix arhgdib cna copy crc cxcl6 deployed integrating loc440995 oit3 omics organizing rab12 ralbp1 rnmt s1000a2 s100a2 sty tokyo tyms ugt2b28 written