ARFIP1 and ARF3

Number of citations of the paper that reports this interaction (PubMedID 10413101)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		ARFIP1	ARF3
Description		ARF interacting protein 1	ARF GTPase 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cytosol Membrane Trans-Golgi Network Membrane	Golgi Membrane Cytoplasm Golgi Apparatus Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Phospholipid Binding Protein Domain Specific Binding Phosphatidylinositol-4-phosphate Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Intracellular Protein Transport Intracellular Protein Localization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Protein Secretion Negative Regulation Of Retrograde Transport, Endosome To Golgi	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Vesicle-mediated Transport
Pathways			Synthesis of PIPs at the Golgi membrane COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean platelet volume ( 32888494) Red cell distribution width ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Bipolar disorder ( 31043756) Heel bone mineral density ( 30598549)
Interacting Genes		18 interacting genes: AFF1 ARF1 ARF3 ARF5 BSND CMTM5 DESI2 KRT27 KRT33B MAGEA6 RPRM SCAMP1 SFT2D1 SLC2A4 SMIM5 SMPD2 SYNGR3 TNFRSF10D	18 interacting genes: APBA1 APBA2 APBA3 ARFIP1 ARFIP2 ATN1 GGA1 GGA2 GGA3 GORAB KIF23 LINC00632 LNX1 PICK1 SCYL1 SLC2A4 SNCA SUMO2
Entrez ID		27236	377
HPRD ID		09331	00056
Ensembl ID		ENSG00000164144	ENSG00000134287
Uniprot IDs		B4E273 P53367 Q8N8M9	P61204
PDB IDs			6II6 8P50
Enriched GO Terms of Interacting Partners?			Protein Domain Specific Binding Protein Transport Intracellular Protein Transport Intracellular Protein Localization Establishment Of Protein Localization Golgi Apparatus Regulation Of Arp2/3 Complex-mediated Actin Nucleation Protein Localization To Cell Surface Membrane Curvature Sensor Activity Regulation Of Actin Nucleation Phospholipid Binding Golgi To Plasma Membrane Protein Transport Establishment Of Protein Localization To Plasma Membrane Regulation Of Protein Catabolic Process Trans-Golgi Network Golgi To Plasma Membrane Transport Perinuclear Region Of Cytoplasm Presynapse Amyloid-beta Binding Establishment Of Localization In Cell Intracellular Transport Ubiquitin Binding Post-Golgi Vesicle-mediated Transport Multicellular Organism Growth Trans-Golgi Network Membrane Small GTPase Binding Golgi Vesicle Transport Phosphatidylinositol Binding Protein Localization To Membrane Chemical Synaptic Transmission Synaptic Vesicle Vesicle-mediated Transport To The Plasma Membrane Trans-synaptic Signaling Monoamine Transport Phosphatidylinositol-4-phosphate Binding Synaptic Signaling Dendritic Spine Regulation Of Supramolecular Fiber Organization Cellular Localization Presynaptic Modulation Of Chemical Synaptic Transmission Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Retrograde Transport, Endosome To Golgi Locomotory Behavior
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