ARFIP1 and SMIM5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARFIP1	SMIM5
Description		ARF interacting protein 1	small integral membrane protein 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cytosol Membrane Trans-Golgi Network Membrane	Membrane
	Molecular Function	Protein Binding Phospholipid Binding Protein Domain Specific Binding Phosphatidylinositol-4-phosphate Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Intracellular Protein Localization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Protein Secretion Negative Regulation Of Retrograde Transport, Endosome To Golgi
Pathways
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean platelet volume ( 32888494) Red cell distribution width ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		18 interacting genes: AFF1 ARF1 ARF3 ARF5 BSND CMTM5 DESI2 KRT27 KRT33B MAGEA6 RPRM SCAMP1 SFT2D1 SLC2A4 SMIM5 SMPD2 SYNGR3 TNFRSF10D	7 interacting genes: ARFIP1 EHHADH PRRT2 RBFA SGTA SH3GLB1 ZFYVE21
Entrez ID		27236	643008
HPRD ID		09331
Ensembl ID		ENSG00000164144	ENSG00000204323
Uniprot IDs		B4E273 P53367 Q8N8M9	Q71RC9
PDB IDs
Enriched GO Terms of Interacting Partners?			Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds TRC Complex Negative Regulation Of Retrograde Transport, Endosome To Golgi Protein Localization To Vacuolar Membrane Negative Regulation Of Short-term Synaptic Potentiation Negative Regulation Of SNARE Complex Assembly Regulation Of Calcium-dependent Activation Of Synaptic Vesicle Fusion Delta(3)-delta(2)-enoyl-CoA Isomerase Activity BAT3 Complex Binding 'de Novo' Post-translational Protein Folding Positive Regulation Of Membrane Tubulation Negative Regulation Of Vesicle Fusion Autophagic Cell Death Enoyl-CoA Hydratase Activity (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Negative Regulation Of ERAD Pathway Regulation Of Retrograde Transport, Endosome To Golgi Phosphatidylinositol 3-kinase Activator Activity 3-hydroxyacyl-CoA Dehydratase Activity
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