SIGLEC9 and LGALS3BP

Number of citations of the paper that reports this interaction (PubMedID 25320078)
66

Data Source:
BioGRID (pull down)

		SIGLEC9	LGALS3BP
Description		sialic acid binding Ig like lectin 9	galectin 3 binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Secretory Granule Membrane	Extracellular Region Extracellular Space Membrane Extracellular Matrix Platelet Dense Granule Lumen Extracellular Exosome Blood Microparticle
	Molecular Function	Protein Binding Carbohydrate Binding Sialic Acid Binding	Scavenger Receptor Activity Protein Binding
	Biological Process	Cell Adhesion Cell Surface Receptor Signaling Pathway	Cellular Defense Response Cell Adhesion Signal Transduction Vesicle-mediated Transport
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation	Platelet degranulation
Drugs
Diseases
GWAS		Body mass index ( 29273807) Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 27863252 32888494) Neurological blood protein biomarker levels ( 31320639)	Blood protein levels ( 30072576)
Interacting Genes		4 interacting genes: BRICD5 LGALS3BP NCS1 SFTPC	24 interacting genes: CD14 COL5A1 COL6A1 FBXO7 FN1 GALNT6 HSP90AA1 ITGA5 ITGA6 ITGAV ITGB1 LGALS1 LGALS3 NID1 PPIC SELE SIGLEC10 SIGLEC11 SIGLEC5 SIGLEC6 SIGLEC7 SIGLEC9 WNT4 XRN1
Entrez ID		27180	3959
HPRD ID		16133	02796
Ensembl ID		ENSG00000129450	ENSG00000108679
Uniprot IDs		Q9Y336	Q08380
PDB IDs			1BY2 6GFB
Enriched GO Terms of Interacting Partners?		Extracellular Space Lamellar Body Multivesicular Body Lumen Alveolar Lamellar Body Calcium Sensitive Guanylate Cyclase Activator Activity Mitochondrial Intermembrane Space Chaperone Complex	Cell Adhesion Sialic Acid Binding Carbohydrate Binding Wound Healing, Spreading Of Epidermal Cells Cell-matrix Adhesion Laminin Binding Integrin Complex Cell-substrate Adhesion Wound Healing, Spreading Of Cells Response To Muscle Activity Endodermal Cell Differentiation Integrin-mediated Signaling Pathway Proteoglycan Binding Regulation Of Cellular Component Organization Plasma Membrane Extracellular Matrix Cell Surface Cell Migration Integrin Binding Integrin Alpha6-beta1 Complex Integrin Alpha5-beta1 Complex Integrin Alphav-beta1 Complex Response To Activity Positive Regulation Of Cell Adhesion Cell Motility Basement Membrane Positive Regulation Of Cell Migration Regulation Of Locomotion Cell Adhesion Mediated By Integrin Regulation Of Cell Adhesion Secretory Granule Membrane Positive Regulation Of Cell Motility Calcium-independent Cell-matrix Adhesion Positive Regulation Of Locomotion Basement Membrane Organization Negative Regulation Of Apoptotic Signaling Pathway Heterotypic Cell-cell Adhesion Neuregulin Binding C-X3-C Chemokine Binding Cell-substrate Junction Assembly Cell-substrate Junction Organization Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Dendritic Cell Differentiation Signaling Receptor Activity Regulation Of Cell Migration Cell-cell Adhesion Mediated By Integrin Extracellular Exosome Endoplasmic Reticulum Lumen Extracellular Region Regulation Of Cell Motility
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