GJB1 and CNST

Number of citations of the paper that reports this interaction (PMID 19864490)
10

Data Source:
BioGRID (pull down)

		GJB1	CNST
Gene Name		gap junction protein, beta 1, 32kDa	consortin, connexin sorting protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Connexon Complex Integral Component Of Membrane	Trans-Golgi Network Plasma Membrane Membrane Integral Component Of Membrane Transport Vesicle Protein Complex
	Molecular Function	Protein Homodimerization Activity	Protein Binding Phosphatase Binding Connexin Binding
	Biological Process	Transport Cell-cell Signaling Nervous System Development Gap Junction Assembly Membrane Organization	Negative Regulation Of Phosphatase Activity Positive Regulation Of Golgi To Plasma Membrane Protein Transport
Pathways		Gap junction assembly Transport of connexins along the secretory pathway Gap junction trafficking and regulation Gap junction trafficking Oligomerization of connexins into connexons
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: APP CALM1 CNST GJB2 PRKACA PRKCA SRC VKORC1	11 interactors: EWSR1 GJA1 GJB1 GJB2 GJB3 GJB6 GJC1 POT1 PPP1CA PPP1CC ROPN1
Entrez ID		2705	163882
HPRD ID		02367	08718
Ensembl ID		ENSG00000169562	ENSG00000162852
Uniprot IDs		P08034	Q6PJW8
PDB IDs		1TXH
Enriched GO Terms of Interacting Partners?		Blood Coagulation Hemostasis Platelet Activation Regulation Of Body Fluid Levels Wound Healing Response To Wounding Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Activation Of Adenylate Cyclase Activity Positive Regulation Of Dense Core Granule Biogenesis Rhodopsin Mediated Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Adenylate Cyclase Activity Cellular Response To Fibroblast Growth Factor Stimulus Histone H3-T6 Phosphorylation Response To Fibroblast Growth Factor Positive Regulation Of Lyase Activity Cell-cell Junction Organization Neurotrophin TRK Receptor Signaling Pathway Activation Of Phospholipase C Activity Neurotrophin Signaling Pathway Regulation Of Adenylate Cyclase Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of CAMP Biosynthetic Process Cell Activation Regulation Of Insulin Receptor Signaling Pathway Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Cell Cycle Regulation Of Protein Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Phospholipase Activity Phototransduction, Visible Light Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of Cellular Response To Insulin Stimulus Innate Immune Response Positive Regulation Of Cyclic Nucleotide Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Response To Interleukin-1 Regulation Of Phospholipase Activity Regulation Of CAMP Biosynthetic Process Response To Light Stimulus Positive Regulation Of Lipase Activity Detection Of Visible Light Membrane Organization	Gap Junction Assembly Cell-cell Junction Assembly Cell Junction Assembly Cell-cell Junction Organization Atrial Cardiac Muscle Cell Action Potential Atrial Cardiac Muscle Cell To AV Node Cell Communication Cell-cell Signaling Involved In Cardiac Conduction Response To Glucose Triglyceride Catabolic Process Sensory Perception Of Sound Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of DNA Biosynthetic Process Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Sensory Perception Of Mechanical Stimulus Response To Carbohydrate Cardiac Muscle Cell Action Potential Involved In Contraction Cardiac Muscle Cell Action Potential Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Regulation Of DNA Biosynthetic Process Response To Organic Substance Sensory Perception Glycogen Metabolic Process Membrane Organization Cell Communication Cell-cell Signaling System Development Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of DNA Strand Elongation Response To Human Chorionic Gonadotropin Milk Ejection Vascular Transport Regulation Of Cardiac Muscle Contraction Circadian Regulation Of Gene Expression Organ Development Polysaccharide Metabolic Process Cellular Component Assembly Action Potential Regulation Of Striated Muscle Contraction Triglyceride Metabolic Process Response To Abiotic Stimulus Regulation Of Circadian Rhythm Negative Regulation Of DNA Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Atrial Ventricular Junction Remodeling Positive Regulation Of Cell Communication By Chemical Coupling Multicellular Organismal Development Neutral Lipid Metabolic Process
Tagcloud ?		aberrantly aberration ap1s2 brcc3 cpxcr1 cxorf45 ddx53 dmd fam9a fhl1 gabre hdac8 hypermethylated hypomethylated hypomethylation hysterectomy irreversible leiomyoma leiomyomas myometrium nxf5 paired pcdh11x ream taf1 tag uterine vbp1 xist	advance canadian completion confirms coordinators criterion dietitians doi dt ejcn exploratory item journal nutrition palliative personnel predicts publication rater readmission reliability subsample technician tool untrained validity wards x2 yes
Tagcloud (Difference) ?		aberrantly aberration ap1s2 brcc3 cpxcr1 cxorf45 ddx53 dmd fam9a fhl1 gabre hdac8 hypermethylated hypomethylated hypomethylation hysterectomy irreversible leiomyoma leiomyomas myometrium nxf5 paired pcdh11x ream taf1 tag uterine vbp1 xist	advance canadian completion confirms coordinators criterion dietitians doi dt ejcn exploratory item journal nutrition palliative personnel predicts publication rater readmission reliability subsample technician tool untrained validity wards x2 yes
Tagcloud (Intersection) ?