CNST and GJB2

Number of citations of the paper that reports this interaction (PMID 19864490)
10

Data Source:
BioGRID (pull down)

		CNST	GJB2
Gene Name		consortin, connexin sorting protein	gap junction protein, beta 2, 26kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Trans-Golgi Network Plasma Membrane Membrane Integral Component Of Membrane Transport Vesicle Protein Complex	Endoplasmic Reticulum-Golgi Intermediate Compartment Plasma Membrane Connexon Complex Integral Component Of Membrane Lateral Plasma Membrane
	Molecular Function	Protein Binding Phosphatase Binding Connexin Binding	Gap Junction Channel Activity
	Biological Process	Negative Regulation Of Phosphatase Activity Positive Regulation Of Golgi To Plasma Membrane Protein Transport	Transport Cell-cell Signaling Sensory Perception Of Sound Gap Junction Assembly Male Genitalia Development Response To Estradiol Response To Progesterone Cellular Response To Oxidative Stress Response To Human Chorionic Gonadotropin Decidualization Transmembrane Transport Membrane Organization
Pathways			Transport of connexons to the plasma membrane Gap junction assembly Transport of connexins along the secretory pathway Gap junction trafficking and regulation Gap junction trafficking Oligomerization of connexins into connexons
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: EWSR1 GJA1 GJB1 GJB2 GJB3 GJB6 GJC1 POT1 PPP1CA PPP1CC ROPN1	5 interactors: CAV1 CD14 CNST GJB1 GJB6
Entrez ID		163882	2706
HPRD ID		08718	00413
Ensembl ID		ENSG00000162852	ENSG00000165474
Uniprot IDs		Q6PJW8	H9U1J4 P29033
PDB IDs			1XIR 2ZW3 3IZ1 3IZ2
Enriched GO Terms of Interacting Partners?		Gap Junction Assembly Cell-cell Junction Assembly Cell Junction Assembly Cell-cell Junction Organization Atrial Cardiac Muscle Cell Action Potential Atrial Cardiac Muscle Cell To AV Node Cell Communication Cell-cell Signaling Involved In Cardiac Conduction Response To Glucose Triglyceride Catabolic Process Sensory Perception Of Sound Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of DNA Biosynthetic Process Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Sensory Perception Of Mechanical Stimulus Response To Carbohydrate Cardiac Muscle Cell Action Potential Involved In Contraction Cardiac Muscle Cell Action Potential Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Regulation Of DNA Biosynthetic Process Response To Organic Substance Sensory Perception Glycogen Metabolic Process Membrane Organization Cell Communication Cell-cell Signaling System Development Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of DNA Strand Elongation Response To Human Chorionic Gonadotropin Milk Ejection Vascular Transport Regulation Of Cardiac Muscle Contraction Circadian Regulation Of Gene Expression Organ Development Polysaccharide Metabolic Process Cellular Component Assembly Action Potential Regulation Of Striated Muscle Contraction Triglyceride Metabolic Process Response To Abiotic Stimulus Regulation Of Circadian Rhythm Negative Regulation Of DNA Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Atrial Ventricular Junction Remodeling Positive Regulation Of Cell Communication By Chemical Coupling Multicellular Organismal Development Neutral Lipid Metabolic Process	Response To Electrical Stimulus Regulation Of Vesicle-mediated Transport Regulation Of Membrane Repolarization During Action Potential Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Transport Nitric Oxide Homeostasis Response To Lipid Regulation Of Endocytosis Positive Regulation Of Golgi To Plasma Membrane Protein Transport Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of Inward Rectifier Potassium Channel Activity Apoptotic Process Programmed Cell Death Regulation Of Cellular Localization Negative Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Negative Regulation Of Pinocytosis Cell Death Death Response To Abiotic Stimulus Caveolin-mediated Endocytosis Protein Localization To Basolateral Plasma Membrane Mammary Gland Involution Positive Regulation Of Intracellular Transport Protein Localization To Plasma Membrane Raft Positive Regulation Of Metalloenzyme Activity Caveola Assembly Regulation Of Cardiac Muscle Cell Action Potential Regulation Of The Force Of Heart Contraction By Chemical Signal Response To Lipopolysaccharide Negative Regulation Of Nitric-oxide Synthase Activity Response To Metal Ion Response To Molecule Of Bacterial Origin Cellular Response To Hyperoxia Regulation Of Golgi To Plasma Membrane Protein Transport Positive Regulation Of Protein Transport Membrane Raft Assembly Protein Localization To Membrane Raft Negative Regulation Of Monooxygenase Activity Negative Regulation Of Protein Autophosphorylation Negative Regulation Of Potassium Ion Transmembrane Transport Cellular Response To Lipoteichoic Acid Negative Regulation Of Anoikis Negative Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Intracellular Transport Response To Magnesium Ion Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Anoikis Response To Inorganic Substance
Tagcloud ?		advance canadian completion confirms coordinators criterion dietitians doi dt ejcn exploratory item journal nutrition palliative personnel predicts publication rater readmission reliability subsample technician tool untrained validity wards x2 yes	12s audiometry brainstem clinics counseling deaf deafness del etiologies gjb3 guidance hearing hereditary heterozygous homozygous hot liaoning mutation occupies profound questionnaires rrna slc26a4 spot syndromic templates theoretical tone tympanometry
Tagcloud (Difference) ?		advance canadian completion confirms coordinators criterion dietitians doi dt ejcn exploratory item journal nutrition palliative personnel predicts publication rater readmission reliability subsample technician tool untrained validity wards x2 yes	12s audiometry brainstem clinics counseling deaf deafness del etiologies gjb3 guidance hearing hereditary heterozygous homozygous hot liaoning mutation occupies profound questionnaires rrna slc26a4 spot syndromic templates theoretical tone tympanometry
Tagcloud (Intersection) ?