ATP2C1 and GTF2IRD1

Number of citations of the paper that reports this interaction (PubMedID 26275350)
0

Data Source:
BioGRID (two hybrid)

		ATP2C1	GTF2IRD1
Description		ATPase secretory pathway Ca2+ transporting 1	GTF2I repeat domain containing 1
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Plasma Membrane Endomembrane System Membrane Golgi Cisterna Membrane Cis-Golgi Network Membrane	Nucleus Nucleoplasm Cytosol
	Molecular Function	Nucleotide Binding P-type Calcium Transporter Activity Calcium Ion Binding ATP Binding ATP Hydrolysis Activity Manganese Ion Binding Metal Ion Binding P-type Manganese Transporter Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Manganese Ion Transport Intracellular Calcium Ion Homeostasis Epidermis Development Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Intracellular Manganese Ion Homeostasis Actin Cytoskeleton Organization Golgi Calcium Ion Homeostasis Golgi Calcium Ion Transport Positive Regulation Of Golgi To Plasma Membrane Protein Transport Positive Regulation Of Canonical NF-kappaB Signal Transduction Calcium Ion Transmembrane Transport Manganese Ion Transmembrane Transport Trans-Golgi Network Membrane Organization	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Transcription By RNA Polymerase II Transition Between Slow And Fast Fiber
Pathways		Ion transport by P-type ATPases
Drugs		Enflurane Isoflurane Ritodrine Methoxyflurane Desflurane Sevoflurane Calcium
Diseases		Hailey-Hailey disease; Benign familial pemphigus
GWAS		Refractive error ( 32231278) Restless legs syndrome ( 29029846) Waist circumference ( 28552196)	Age at suicide ( 31476763) Aluminium levels ( 26025379) General factor of neuroticism ( 30867560) Neuroticism ( 29255261) Rheumatoid arthritis ( 32723749) Severe influenza A (H1N1) infection ( 26379185) Sjögren's syndrome ( 24097066) Systemic lupus erythematosus ( 26663301 28714469) Triglyceride levels ( 32203549)
Interacting Genes		3 interacting genes: F2RL1 GPR35 GTF2IRD1	24 interacting genes: ALMS1 ATP2C1 CDK20 DCAF6 EXOSC4 GORASP2 HDAC3 HTRA4 KPNA1 KPNA2 KPNA3 KPNA4 MRFAP1L1 PIAS1 PIAS2 PIP4P2 PKP1 PKP2 SELENOS SMAD3 SPTLC1 UBC USP20 ZMYM5
Entrez ID		27032	9569
HPRD ID		05089	08379
Ensembl ID		ENSG00000017260	ENSG00000006704
Uniprot IDs		B4E295 B4E2Q0 P98194	E9PFE2 Q9UHL9
PDB IDs		7YAG 7YAH 7YAI 7YAJ 7YAM 8IWP 8IWR 8IWS 8IWT 8IWU 8IWW	2D99 2DN5 2DZQ 2DZR
Enriched GO Terms of Interacting Partners?		Coagulation Blood Coagulation Hemostasis Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Negative Regulation Of Transport Positive Regulation Of Renin Secretion Into Blood Stream Gamma-glutamyl Carboxylase Activity Transition Between Slow And Fast Fiber Proteinase-activated Receptor Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Secretion By Cell Positive Regulation Of Eosinophil Degranulation Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Vitamin Binding Negative Regulation Of Bone Development Positive Regulation Of Glomerular Filtration Negative Regulation Of Secretion Regulation Of Renin Secretion Into Blood Stream Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Testosterone Biosynthetic Process Positive Regulation Of Killing Of Cells Of Another Organism Mature Conventional Dendritic Cell Differentiation Thrombin-activated Receptor Activity Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Cytotoxicity Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Regulation Of Body Fluid Levels Regulation Of Testosterone Biosynthetic Process Negative Regulation Of Neurotransmitter Secretion C-X-C Chemokine Receptor Activity Negative Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Toll-like Receptor 3 Signaling Pathway Thrombin-activated Receptor Signaling Pathway Positive Regulation Of Defense Response To Bacterium Positive Regulation Of Actin Filament Depolymerization Positive Regulation Of Pseudopodium Assembly G Protein-coupled Receptor Activity Positive Regulation Of Phagocytosis, Engulfment Regulation Of Transport Regulation Of Glomerular Filtration Regulation Of Bone Development Vitamin K Metabolic Process Regulation Of Skeletal Muscle Adaptation Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Defense Response To Bacterium Pseudopodium Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Positive Regulation Of Protein Depolymerization Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure	NLS-dependent Protein Nuclear Import Complex Nuclear Import Signal Receptor Activity Nuclear Localization Sequence Binding NLS-bearing Protein Import Into Nucleus Viral Penetration Into Host Nucleus Protein Import Into Nucleus Import Into Nucleus Intermediate Filament Binding Intracellular Transport Of Virus Intermediate Filament Bundle Assembly Desmosome Assembly Nucleoplasm Host Cell Protein Localization To Nucleus SUMO Ligase Activity Positive Regulation Of Protein Localization To Cell Periphery Desmosome Organization Nuclear Pore Ubiquitin-specific Protease Binding Positive Regulation Of Protein Localization SUMO Transferase Activity Nuclear Transport Nucleocytoplasmic Transport SMAD Protein Signal Transduction Desmosome Ubiquitin Protein Ligase Binding Intracellular Protein Transport Cellular Localization Collagen Type XV Trimer Establishment Of Protein Localization To Organelle Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Positive Regulation Of Protein Import Into Nucleus Regulation Of Protein Localization To Cell Periphery Maintenance Of Protein Localization At Cell Tip Positive Regulation Of Ferroptosis
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