RPS6KC1 and PRDX3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)
HPRD (in vivo, two hybrid, in vitro)

		RPS6KC1	PRDX3
Description		ribosomal protein S6 kinase C1	peroxiredoxin 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Early Endosome Membrane Organelle	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix Endosome Early Endosome Cytosol Plasma Membrane Protein-containing Complex
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Lipid Binding Kinase Activity Transferase Activity Phosphatidylinositol Binding Protein Serine Kinase Activity	Peroxidase Activity Protein Binding Thioredoxin Peroxidase Activity Antioxidant Activity Oxidoreductase Activity Protein Kinase Binding Identical Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Peroxiredoxin Activity NADH-dependent Peroxiredoxin Activity Thioredoxin-dependent Peroxiredoxin Activity
	Biological Process	Signal Transduction	Maternal Placenta Development Response To Oxidative Stress Mitochondrion Organization Positive Regulation Of Cell Population Proliferation Myeloid Cell Differentiation Response To Lipopolysaccharide Negative Regulation Of Kinase Activity Cellular Response To Oxidative Stress Cellular Response To Reactive Oxygen Species Response To Hydrogen Peroxide Hydrogen Peroxide Catabolic Process Negative Regulation Of Apoptotic Process Cell Redox Homeostasis Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Mitochondrial Membrane Potential Cellular Oxidant Detoxification
Pathways			Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Breast cancer in childhood cancer survivors ( 29059430) Breast cancer in childhood cancer survivors treated with less than 10 gray radiotherapy ( 29059430) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) Interleukin-6 levels in HIV infection ( 33095540) Refractive error ( 32231278)	Alcoholic chronic pancreatitis ( 28754779)
Interacting Genes		5 interacting genes: PBX2 PRDX3 SAAL1 SPHK1 VDR	15 interacting genes: CDC42 CUL4B FANCC GORASP2 HNRNPD MAGEA11 MAP3K13 NEK6 NR3C1 PRDX4 PTEN RPS6KC1 SUMO4 TNFRSF1A ZNF77
Entrez ID		26750	10935
HPRD ID		10204	05305
Ensembl ID		ENSG00000136643	ENSG00000165672
Uniprot IDs		A0A087X1U5 F5H7T0 F6RJM5 Q96S38	A0A384MTR2 P30048
PDB IDs			5JCG 5UCX
Enriched GO Terms of Interacting Partners?		Maternal Process Involved In Female Pregnancy Negative Regulation Of Phosphate Transmembrane Transport Calcitriol Binding Nuclear Receptor-mediated Bile Acid Signaling Pathway Bile Acid Nuclear Receptor Activity Regulation Of Cell Population Proliferation Lithocholic Acid Binding Sphingoid Catabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Cellular Response To Reactive Oxygen Species Response To Hydrogen Peroxide Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Endosomal Vesicle Fusion NADH-dependent Peroxiredoxin Activity Apoptotic Process Involved In Mammary Gland Involution Vitamin D Response Element Binding Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Mammary Gland Branching Involved In Pregnancy Vitamin D Receptor Signaling Pathway Sphingosine Kinase Activity Regulation Of DNA-binding Transcription Factor Activity Response To Reactive Oxygen Species Positive Regulation Of Synoviocyte Proliferation Positive Regulation Of Vitamin D Receptor Signaling Pathway Response To Bile Acid Vitamin D Binding Negative Regulation Of Ceramide Biosynthetic Process Positive Regulation Of Cell Population Proliferation Negative Regulation Of Sphingolipid Biosynthetic Process Lipid Kinase Activity Cellular Response To Oxidative Stress Thioredoxin-dependent Peroxiredoxin Activity Peroxiredoxin Activity Thioredoxin Peroxidase Activity Brain Development Positive Regulation Of Apoptotic Process Involved In Morphogenesis Positive Regulation Of Apoptotic Process Involved In Development Cellular Response To Chemical Stress Regulation Of Phosphate Transport Sphingosine-1-phosphate Receptor Activity Regulation Of Vitamin D Receptor Signaling Pathway Positive Regulation Of Peptidyl-threonine Phosphorylation Maternal Placenta Development Phosphate Ion Transmembrane Transport Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Branching Involved In Mammary Gland Duct Morphogenesis Regulation Of Epithelial Cell Proliferation Regulation Of Programmed Cell Death Nuclear Retinoid X Receptor Binding	Maternal Behavior Parental Behavior Dendritic Spine Morphogenesis Regulation Of Mitotic Cell Cycle Protein Kinase Binding Macrophage Differentiation Neuron Projection Organization Dendritic Spine Organization Postsynapse Organization Response To Stress Astrocyte Differentiation Nuclear Glucocorticoid Receptor Activity Reproductive Behavior Response To Electrical Stimulus Hepatocyte Dedifferentiation Cellular Response To Putrescine Regulation Of Cellular Senescence Negative Regulation Of Synaptic Vesicle Clustering Positive Regulation Of Branching Morphogenesis Of A Nerve
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?