RPS6KC1 and SAAL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RPS6KC1	SAAL1
Description		ribosomal protein S6 kinase C1	serum amyloid A like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Early Endosome Membrane Organelle	Nucleus Nucleoplasm
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Lipid Binding Kinase Activity Transferase Activity Phosphatidylinositol Binding Protein Serine Kinase Activity
	Biological Process	Signal Transduction	Positive Regulation Of Synoviocyte Proliferation
Pathways
Drugs
Diseases
GWAS		Breast cancer in childhood cancer survivors ( 29059430) Breast cancer in childhood cancer survivors treated with less than 10 gray radiotherapy ( 29059430) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) Interleukin-6 levels in HIV infection ( 33095540) Refractive error ( 32231278)
Interacting Genes		5 interacting genes: PBX2 PRDX3 SAAL1 SPHK1 VDR	17 interacting genes: AMOTL2 C1orf87 DMAP1 MARK3 NEDD4 OGT PRRX1 RPH3AL RPS6KC1 SNAPC1 SNW1 SSX7 TCP10L TSGA10IP ZNF443 ZNF57 ZNF620
Entrez ID		26750	113174
HPRD ID		10204	13999
Ensembl ID		ENSG00000136643	ENSG00000166788
Uniprot IDs		A0A087X1U5 F5H7T0 F6RJM5 Q96S38	G1UCX3 Q96ER3
PDB IDs
Enriched GO Terms of Interacting Partners?		Maternal Process Involved In Female Pregnancy Negative Regulation Of Phosphate Transmembrane Transport Calcitriol Binding Nuclear Receptor-mediated Bile Acid Signaling Pathway Bile Acid Nuclear Receptor Activity Regulation Of Cell Population Proliferation Lithocholic Acid Binding Sphingoid Catabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Cellular Response To Reactive Oxygen Species Response To Hydrogen Peroxide Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Endosomal Vesicle Fusion NADH-dependent Peroxiredoxin Activity Apoptotic Process Involved In Mammary Gland Involution Vitamin D Response Element Binding Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Mammary Gland Branching Involved In Pregnancy Vitamin D Receptor Signaling Pathway Sphingosine Kinase Activity Regulation Of DNA-binding Transcription Factor Activity Response To Reactive Oxygen Species Positive Regulation Of Synoviocyte Proliferation Positive Regulation Of Vitamin D Receptor Signaling Pathway Response To Bile Acid Vitamin D Binding Negative Regulation Of Ceramide Biosynthetic Process Positive Regulation Of Cell Population Proliferation Negative Regulation Of Sphingolipid Biosynthetic Process Lipid Kinase Activity Cellular Response To Oxidative Stress Thioredoxin-dependent Peroxiredoxin Activity Peroxiredoxin Activity Thioredoxin Peroxidase Activity Brain Development Positive Regulation Of Apoptotic Process Involved In Morphogenesis Positive Regulation Of Apoptotic Process Involved In Development Cellular Response To Chemical Stress Regulation Of Phosphate Transport Sphingosine-1-phosphate Receptor Activity Regulation Of Vitamin D Receptor Signaling Pathway Positive Regulation Of Peptidyl-threonine Phosphorylation Maternal Placenta Development Phosphate Ion Transmembrane Transport Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Branching Involved In Mammary Gland Duct Morphogenesis Regulation Of Epithelial Cell Proliferation Regulation Of Programmed Cell Death Nuclear Retinoid X Receptor Binding	Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II
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