NPAS4 and ARNT2

Number of citations of the paper that reports this interaction (PMID 14701734)
30

Data Source:
HPRD (two hybrid)

		NPAS4	ARNT2
Gene Name		neuronal PAS domain protein 4	aryl-hydrocarbon receptor nuclear translocator 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Nucleus Transcription Factor Complex Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Signal Transducer Activity Protein Heterodimerization Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Signal Transducer Activity Aryl Hydrocarbon Receptor Binding Protein Heterodimerization Activity
	Biological Process	Transcription, DNA-templated Signal Transduction Positive Regulation Of Transcription From RNA Polymerase II Promoter	Response To Hypoxia In Utero Embryonic Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Signal Transduction Central Nervous System Development Brain Development Positive Regulation Of Cell Proliferation Response To Estradiol Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		3 interactors: ARNT ARNT2 ARNTL	59 interactors: ADAMTSL4 APP ARNT BZRAP1 CALCOCO2 CCDC33 CDR2 CEP57L1 CEP63 CTBP1 DGCR6 DTX2 DYDC1 EPAS1 GOLGA2 HIF1A IKZF3 KIFC3 LZTS2 MAGEA4 MEIS2 MEOX2 MIPOL1 MTUS2 NCOA3 NDE1 NPAS2 NPAS3 NPAS4 PDE4DIP PLSCR1 RBCK1 REL RFX6 RIMBP3 RINT1 SH3GL2 SIM2 SORBS3 SPAG5 SSBP3 SSX2IP SYCE1 TACC3 TADA2A TAX1BP3 TFIP11 TRAF1 TRAF2 TRAF4 TRIM23 TRIM27 TRIM37 TRIM42 TRIP6 USHBP1 USP7 VPS52 ZNF341
Entrez ID		266743	9915
HPRD ID		12260	06915
Ensembl ID		ENSG00000174576	ENSG00000172379
Uniprot IDs		Q8IUM7	Q7Z3A3 Q86TN1 Q9HBZ2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Cellular Response To Oxidative Stress Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Response To Hypoxia Oxidative Stress-induced Premature Senescence Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Skeletal Muscle Cell Differentiation Stress-induced Premature Senescence Response To Oxidative Stress Transcription, DNA-templated Negative Regulation Of Glucocorticoid Receptor Signaling Pathway RNA Biosynthetic Process Response To Redox State Positive Regulation Of Cellular Metabolic Process Regulation Of Type B Pancreatic Cell Development In Utero Embryonic Development Positive Regulation Of Hormone Biosynthetic Process MRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of Glycolytic Process Positive Regulation Of Protein Sumoylation Regulation Of Skeletal Muscle Cell Differentiation Positive Regulation Of Circadian Rhythm MRNA Transcription Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Regulation Of Protein Sumoylation RNA Metabolic Process Positive Regulation Of Erythrocyte Differentiation Regulation Of Cellular Senescence Regulation Of Hair Cycle Positive Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Response To Stress Gene Expression Cellular Senescence Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Protein Import Into Nucleus, Translocation Regulation Of Glycolytic Process Regulation Of Hormone Biosynthetic Process Positive Regulation Of Cell Proliferation Cellular Macromolecule Biosynthetic Process Negative Regulation Of TOR Signaling Positive Regulation Of Cell Differentiation Macromolecule Biosynthetic Process Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway	Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Gene Expression Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Microtubule-based Process Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Protein Localization Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Cellular Localization Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Positive Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Cellular Process Regulation Of Signal Transduction Microtubule Cytoskeleton Organization Regulation Of Signaling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process NIK/NF-kappaB Signaling Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Organ Development Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Component Assembly Embryonic Placenta Development Organelle Organization Positive Regulation Of NF-kappaB Transcription Factor Activity Spindle Organization Microtubule-based Transport Protein Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Protein Homodimerization Activity Cytoskeleton-dependent Intracellular Transport Regulation Of DNA-templated Transcription In Response To Stress
Tagcloud ?		accumbens acetylated acetyltransferase addiction atf2 causal cck cholecystokinin corticotropin crf deacetylases fosb h3k18ac h3k9ac h4k5 h4k8 hat hats hdac1 hdac2 hdacs injection longterm meth methamphetamine nac neuropsychiatric psychostimulants releasing	adenovirus ahr arises aromatic aryl bhlh cbp conveys dioxin e1a extensively gst heterodimer hlf hybrid hydrocarbon hydrocarbons interacted metabolizing methylcholanthrene partner pas pull sim somehow tetrachlorodibenzo transactivation translocator
Tagcloud (Difference) ?		accumbens acetylated acetyltransferase addiction atf2 causal cck cholecystokinin corticotropin crf deacetylases fosb h3k18ac h3k9ac h4k5 h4k8 hat hats hdac1 hdac2 hdacs injection longterm meth methamphetamine nac neuropsychiatric psychostimulants releasing	adenovirus ahr arises aromatic aryl bhlh cbp conveys dioxin e1a extensively gst heterodimer hlf hybrid hydrocarbon hydrocarbons interacted metabolizing methylcholanthrene partner pas pull sim somehow tetrachlorodibenzo transactivation translocator
Tagcloud (Intersection) ?