OSTF1 and NUTM2F

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		OSTF1	NUTM2F
Description		osteoclast stimulating factor 1	NUT family member 2F
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding SH3 Domain Binding
	Biological Process	Ossification Signal Transduction
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Allergic rhinitis ( 25085501) Glucose homeostasis traits ( 25524916) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Resting-state electroencephalogram vigilance ( 29703947) Systemic sclerosis ( 30247649) Urinary magnesium-to-creatinine ratio ( 29093028)	Appendicular lean mass ( 33097823) Body mass index ( 28892062) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954)
Interacting Genes		51 interacting genes: AGR2 APP BORCS6 CBL CBLB CCDC33 CRX CTDSP1 CUEDC1 DPPA4 DTX3 EFS ERRFI1 FASLG FBXO7 GAPDH GGN HES7 HTT KHDRBS1 KLHL42 LATS1 LMNA MAPK6 MED19 MEOX2 NFYC NUTM1 NUTM2F PBX4 PICK1 PRRG4 REL SDCBP SF1 SF3A2 SMN1 SNW1 SOCS7 SYNGAP1 TRIB3 TRIM54 VPS37B WASF1 WASHC1 WASL YPEL3 ZBTB42 ZBTB7B ZNF655 ZNF688	20 interacting genes: AIRIM ANKS1A ATXN1L FADD GRB2 HGS LENG8 MORN4 NCK1 NCK2 NFYC OSTF1 PRPF18 RAD23A RBM47 SH3GL1 SH3RF1 VPS37C ZMYND10 ZNF148
Entrez ID		26578	54754
HPRD ID		17808	19318
Ensembl ID		ENSG00000134996	ENSG00000130950
Uniprot IDs		Q92882	A1L443
PDB IDs		1X2K 1ZLM 3EHQ 3EHR
Enriched GO Terms of Interacting Partners?		Regulation Of Receptor-mediated Endocytosis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway SH3 Domain Binding Regulation Of ERBB Signaling Pathway Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Synapse Structure Or Activity Regulation Of Receptor Internalization Nucleus Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of ERBB Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway MRNA 3'-splice Site Recognition Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Transcription By RNA Polymerase II Establishment Of Organelle Localization Regulation Of Actin Nucleation Neuron Projection Organization Cytoskeleton-dependent Intracellular Transport Regulation Of Endocytosis Cellular Response To Nerve Growth Factor Stimulus Response To Nerve Growth Factor Positive Regulation Of Cellular Component Organization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Localization Spliceosomal Complex Assembly Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Protein Binding Regulation Of Intracellular Signal Transduction Regulation Of Primary Metabolic Process Regulation Of Signal Transduction Arp2/3 Complex Binding Regulation Of Supramolecular Fiber Organization Regulation Of Metabolic Process Regulation Of Plasma Membrane Organization Negative Regulation Of Alpha-beta T Cell Proliferation Localization Within Membrane Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G1/S Phase Transition Regulation Of RNA Metabolic Process Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Endocytosis Regulation Of Cell Communication Regulation Of Signaling Regulation Of Extrinsic Apoptotic Signaling Pathway	Ephrin Receptor Binding Vesicle Membrane Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Actin Filament Polymerization Ephrin Receptor Signaling Pathway Positive Regulation Of Translation In Response To Stress Signal Complex Assembly Regulation Of Translation In Response To Endoplasmic Reticulum Stress Regulation Of T Cell Proliferation Regulation Of Translational Initiation In Response To Stress Regulation Of T Cell Activation Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of PERK-mediated Unfolded Protein Response Signaling Adaptor Activity Positive Regulation Of Protein Polymerization Regulation Of PERK-mediated Unfolded Protein Response Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of T Cell Activation Positive Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Lymphocyte Activation Cytoskeletal Anchor Activity Positive Regulation Of T Cell Proliferation Regulation Of Translation In Response To Stress Regulation Of Leukocyte Proliferation Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Type I Interferon-mediated Signaling Pathway T Cell Activation Regulation Of Actin Filament Polymerization Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of Cell-cell Adhesion Positive Regulation Of Lymphocyte Activation Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Cell Activation Signaling Receptor Complex Adaptor Activity Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Multivesicular Body Organization Multivesicular Body Assembly Lamellipodium Assembly Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Unfolded Protein Response Late Endosome To Vacuole Transport Positive Regulation Of Supramolecular Fiber Organization Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Cell Activation
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