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PYGO1 and BCL9
Number of citations of the paper that reports this interaction (PubMedID
11955446
)
0
Data Source:
HPRD
(two hybrid, in vitro, in vivo)
PYGO1
BCL9
Description
pygopus family PHD finger 1
BCL9 transcription coactivator
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cis-Golgi Network
Sarcoplasm
Beta-catenin-TCF Complex
Molecular Function
Protein Binding
Zinc Ion Binding
Metal Ion Binding
Histone H3K4me3 Reader Activity
Transcription Coactivator Activity
Protein Binding
Beta-catenin Binding
Biological Process
Kidney Development
Hematopoietic Progenitor Cell Differentiation
Chromatin Organization
Spermatid Development
Spermatid Nucleus Differentiation
Wnt Signaling Pathway
Protein Localization To Nucleus
Positive Regulation Of Transcription By RNA Polymerase II
Canonical Wnt Signaling Pathway
Transcription By RNA Polymerase II
Myotube Differentiation Involved In Skeletal Muscle Regeneration
Wnt Signaling Pathway
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Somatic Stem Cell Population Maintenance
Skeletal Muscle Cell Differentiation
Myoblast Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Canonical Wnt Signaling Pathway
Pathways
Formation of the beta-catenin:TCF transactivating complex
Deactivation of the beta-catenin transactivating complex
Formation of the beta-catenin:TCF transactivating complex
Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS
Appendicular lean mass (
33097823
)
Brain morphology (MOSTest) (
32665545
)
Adult body size (
32376654
)
Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) (
24025145
)
Schizophrenia (negative symptoms) (
23382809
)
Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes (
28736931
)
Type 2 diabetes (
25760438
)
Interacting Genes
6 interacting genes:
BCL9
CARM1
CTNNB1
LENG8
PRMT6
SPTBN1
6 interacting genes:
BCL2L13
CTNNB1
MAP1LC3A
PYGO1
PYGO2
USP9X
Entrez ID
26108
607
HPRD ID
06064
04000
Ensembl ID
ENSG00000171016
ENSG00000116128
Uniprot IDs
Q9Y3Y4
O00512
Q1JQ81
PDB IDs
2VP7
2VPB
2VPD
2VPE
2VPG
2GL7
2VP7
2VPB
2VPD
2VPE
2VPG
3SL9
8Y0P
Enriched GO Terms of Interacting Partners
?
Histone H3R2 Methyltransferase Activity
Histone Arginine N-methyltransferase Activity
Protein-arginine Omega-N Asymmetric Methyltransferase Activity
Protein-arginine N-methyltransferase Activity
Beta-catenin-TCF Complex
Histone Methyltransferase Activity
Transcription Coactivator Activity
Regulation Of Cell Communication
Regulation Of Signal Transduction
Beta-catenin Binding
Regulation Of Signaling
Maintenance Of Cell Number
Muscle Cell Differentiation
Canonical Wnt Signaling Pathway
Stem Cell Population Maintenance
Myotube Differentiation Involved In Skeletal Muscle Regeneration
Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Mesenchymal Stem Cell Differentiation
Oviduct Development
Positive Regulation Of Determination Of Dorsal Identity
Negative Regulation Of Mitotic Cell Cycle, Embryonic
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Beta-catenin-ICAT Complex
Negative Regulation Of Epithelial Cell Differentiation Involved In Kidney Development
Acinar Cell Differentiation
Positive Regulation Of Proteoglycan Biosynthetic Process
Regulation Of Timing Of Anagen
Fungiform Papilla Formation
Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis
Beta-catenin-TCF7L2 Complex
Cellular Response To Indole-3-methanol
Mesenchymal Cell Proliferation Involved In Lung Development
Glial Cell Fate Determination
Astrocyte-dopaminergic Neuron Signaling
Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Central Nervous System Vasculogenesis
Metanephros Morphogenesis
Trachea Morphogenesis
Regulation Of Mitotic Cell Cycle, Embryonic
Renal Inner Medulla Development
Scrib-APC-beta-catenin Complex
Cranial Ganglion Development
Regulation Of Centriole-centriole Cohesion
Renal Outer Medulla Development
Renal Vesicle Formation
Embryonic Skeletal Limb Joint Morphogenesis
Protein-containing Complex
Glial Cell-neuron Signaling
Lung Induction
Regulation Of Centromeric Sister Chromatid Cohesion
Canonical Wnt Signaling Pathway
Spermatid Nucleus Differentiation
Beta-catenin-TCF Complex
Kidney Development
Germ Cell Development
Wnt Signaling Pathway
Mitophagy
Developmental Growth
Mesenchymal Stem Cell Differentiation
Positive Regulation Of Determination Of Dorsal Identity
Negative Regulation Of Mitotic Cell Cycle, Embryonic
Beta-catenin-ICAT Complex
Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis
Reproductive Process
Neuron Projection Extension
Glial Cell Fate Determination
Renal Inner Medulla Development
Scrib-APC-beta-catenin Complex
Renal Outer Medulla Development
Renal Vesicle Formation
Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation
Positive Regulation Of Branching Involved In Lung Morphogenesis
Neural Plate Development
Developmental Cell Growth
Organelle Organization
K11-linked Deubiquitinase Activity
Autophagy Of Mitochondrion
Nucleus Organization
Spermatid Development
Histone Acetyltransferase Regulator Activity
Oviduct Development
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Fungiform Papilla Formation
Beta-catenin-TCF7L2 Complex
Astrocyte-dopaminergic Neuron Signaling
Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Regulation Of Centriole-centriole Cohesion
Embryonic Skeletal Limb Joint Morphogenesis
Lung Induction
Neuron Migration
Catenin-TCF7L2 Complex
Developmental Growth Involved In Morphogenesis
Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Negative Regulation Of Epithelial Cell Differentiation Involved In Kidney Development
Acinar Cell Differentiation
Positive Regulation Of Proteoglycan Biosynthetic Process
Metanephros Morphogenesis
Trachea Morphogenesis
Regulation Of Mitotic Cell Cycle, Embryonic
Glial Cell-neuron Signaling
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