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BCL9
Description
BCL9 transcription coactivator
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cis-Golgi Network
Sarcoplasm
Beta-catenin-TCF Complex
Molecular Function
Transcription Coactivator Activity
Protein Binding
Beta-catenin Binding
Biological Process
Transcription By RNA Polymerase II
Myotube Differentiation Involved In Skeletal Muscle Regeneration
Wnt Signaling Pathway
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Somatic Stem Cell Population Maintenance
Skeletal Muscle Cell Differentiation
Myoblast Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Canonical Wnt Signaling Pathway
Pathways
Formation of the beta-catenin:TCF transactivating complex
Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) (
24025145
)
Schizophrenia (negative symptoms) (
23382809
)
Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes (
28736931
)
Type 2 diabetes (
25760438
)
Interacting Genes
6 interacting genes:
BCL2L13
CTNNB1
MAP1LC3A
PYGO1
PYGO2
USP9X
Entrez ID
607
HPRD ID
04000
Ensembl ID
ENSG00000116128
Uniprot IDs
O00512
Q1JQ81
PDB IDs
2GL7
2VP7
2VPB
2VPD
2VPE
2VPG
3SL9
8Y0P
Enriched GO Terms of Interacting Partners
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Canonical Wnt Signaling Pathway
Spermatid Nucleus Differentiation
Beta-catenin-TCF Complex
Kidney Development
Germ Cell Development
Wnt Signaling Pathway
Mitophagy
Developmental Growth
Mesenchymal Stem Cell Differentiation
Positive Regulation Of Determination Of Dorsal Identity
Negative Regulation Of Mitotic Cell Cycle, Embryonic
Beta-catenin-ICAT Complex
Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis
Reproductive Process
Neuron Projection Extension
Glial Cell Fate Determination
Renal Inner Medulla Development
Scrib-APC-beta-catenin Complex
Renal Outer Medulla Development
Renal Vesicle Formation
Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation
Positive Regulation Of Branching Involved In Lung Morphogenesis
Neural Plate Development
Developmental Cell Growth
Organelle Organization
K11-linked Deubiquitinase Activity
Autophagy Of Mitochondrion
Nucleus Organization
Spermatid Development
Histone Acetyltransferase Regulator Activity
Oviduct Development
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Fungiform Papilla Formation
Beta-catenin-TCF7L2 Complex
Astrocyte-dopaminergic Neuron Signaling
Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Regulation Of Centriole-centriole Cohesion
Embryonic Skeletal Limb Joint Morphogenesis
Lung Induction
Neuron Migration
Catenin-TCF7L2 Complex
Developmental Growth Involved In Morphogenesis
Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Negative Regulation Of Epithelial Cell Differentiation Involved In Kidney Development
Acinar Cell Differentiation
Positive Regulation Of Proteoglycan Biosynthetic Process
Metanephros Morphogenesis
Trachea Morphogenesis
Regulation Of Mitotic Cell Cycle, Embryonic
Glial Cell-neuron Signaling
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