DNAAF6 and BTAF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		DNAAF6	BTAF1
Description		dynein axonemal assembly factor 6	B-TFIID TATA-box binding protein associated factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Trans-Golgi Network	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Dynein Intermediate Chain Binding Protein-folding Chaperone Binding	Nucleotide Binding DNA Binding Transcription Coregulator Activity Helicase Activity ATP Binding ATP-dependent Activity, Acting On DNA Hydrolase Activity ATP Hydrolysis Activity TBP-class Protein Binding
	Biological Process	Cilium Movement Flagellated Sperm Motility Outer Dynein Arm Assembly Inner Dynein Arm Assembly Axonemal Dynein Complex Assembly	Negative Regulation Of Chromatin Binding Negative Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS			Type 2 diabetes ( 32499647)
Interacting Genes		16 interacting genes: ARID4B BTAF1 CCAR1 CDKL3 GAS2L2 KAT5 KIF13A MCM7 P2RX4 PID1 POLDIP2 PRKAA2 QRICH1 RNF39 TSEN15 YAF2	4 interacting genes: DNAAF6 MVD PIAS4 TBP
Entrez ID		139212	9044
HPRD ID		06650	05546
Ensembl ID		ENSG00000080572	ENSG00000095564
Uniprot IDs		Q9NQM4	O14981 Q2M1V9 Q8N6J1
PDB IDs
Enriched GO Terms of Interacting Partners?		Lipid Droplet Disassembly Phosphatidylethanolamine Biosynthetic Process Positive Regulation Of Biosynthetic Process Phosphatidylethanolamine Metabolic Process Phosphatidylcholine Biosynthetic Process CGAS/STING Signaling Pathway	Isopentenyl Diphosphate Biosynthetic Process, Mevalonate Pathway Diphosphomevalonate Decarboxylase Activity Steroid Metabolic Process Isopentenyl Diphosphate Biosynthetic Process Isopentenyl Diphosphate Metabolic Process RNA Polymerase Transcription Factor SL1 Complex TFIIB-class Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Binding Male Pronucleus Transcription Factor TFIIA Complex Aryl Hydrocarbon Receptor Binding Pronucleus RNA Polymerase I Core Promoter Sequence-specific DNA Binding Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Protein Localization To Chromatin Regulation Of Keratinocyte Apoptotic Process Limb Epidermis Development Positive Regulation Of Keratinocyte Apoptotic Process Negative Regulation Of Protein Localization To Chromatin RNA Polymerase I Preinitiation Complex Assembly Female Pronucleus RNA Polymerase III General Transcription Initiation Factor Activity Female Germ Cell Nucleus Vitamin D Metabolic Process SUMO Ligase Activity Transferase Complex Positive Regulation Of Protein Sumoylation Inner Dynein Arm Assembly Core Promoter Sequence-specific DNA Binding Outer Dynein Arm Assembly SUMO Transferase Activity RNA Polymerase II Core Promoter Sequence-specific DNA Binding Carboxy-lyase Activity Positive Regulation Of Epithelial Cell Apoptotic Process Regulation Of Protein Sumoylation Isoprenoid Biosynthetic Process
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