DNAAF6 and ARID4B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DNAAF6	ARID4B
Description		dynein axonemal assembly factor 6	AT-rich interaction domain 4B
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Trans-Golgi Network	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Sin3-type Complex
	Molecular Function	Protein Binding Dynein Intermediate Chain Binding Protein-folding Chaperone Binding	Transcription Cis-regulatory Region Binding DNA Binding Protein Binding
	Biological Process	Cilium Movement Flagellated Sperm Motility Outer Dynein Arm Assembly Inner Dynein Arm Assembly Axonemal Dynein Complex Assembly	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Spermatogenesis Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Genomic Imprinting Establishment Of Sertoli Cell Barrier Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance
Pathways			HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823) Asthma ( 29273806) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Night sleep phenotypes ( 27126917) Plateletcrit ( 32888494)
Interacting Genes		16 interacting genes: ARID4B BTAF1 CCAR1 CDKL3 GAS2L2 KAT5 KIF13A MCM7 P2RX4 PID1 POLDIP2 PRKAA2 QRICH1 RNF39 TSEN15 YAF2	15 interacting genes: DNAAF6 DYNLT1 EAF1 ETS1 HNRNPA2B1 NHSL2 NTAQ1 PIK3R3 PLEKHF2 PRR23B PTGES3L-AARSD1 RANBP2 SAP130 SIN3A SPANXB1
Entrez ID		139212	51742
HPRD ID		06650	10661
Ensembl ID		ENSG00000080572	ENSG00000054267
Uniprot IDs		Q9NQM4	Q4LE39
PDB IDs			7DM4
Enriched GO Terms of Interacting Partners?		Lipid Droplet Disassembly Phosphatidylethanolamine Biosynthetic Process Positive Regulation Of Biosynthetic Process Phosphatidylethanolamine Metabolic Process Phosphatidylcholine Biosynthetic Process CGAS/STING Signaling Pathway	Dynein Intermediate Chain Binding Transport Of Viral Material Towards Nucleus Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Cellular Response To Tert-butyl Hydroperoxide Positive Regulation Of Stem Cell Population Maintenance Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Response To Methylglyoxal Protein-N-terminal Glutamine Amidohydrolase Activity
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