GIGYF2 and RQCD1

Number of citations of the paper that reports this interaction (PMID 20878056)
2

Data Source:
BioGRID (affinity chromatography technology, pull down)

		GIGYF2	RQCD1
Gene Name		GRB10 interacting GYF protein 2	RCD1 required for cell differentiation1 homolog (S. pombe)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Membrane	Cytoplasmic MRNA Processing Body Nucleus Cytosol Membrane CCR4-NOT Complex
	Molecular Function	Poly(A) RNA Binding	Protein Binding Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	Feeding Behavior Adult Locomotory Behavior Post-embryonic Development Negative Regulation Of Translation Spinal Cord Motor Neuron Differentiation Mitotic G1 DNA Damage Checkpoint Multicellular Organism Growth Cellular Protein Metabolic Process Insulin-like Growth Factor Receptor Signaling Pathway Homeostasis Of Number Of Cells Within A Tissue Musculoskeletal Movement Neuromuscular Process Controlling Balance	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Poly(A) Tail Shortening Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Translation Sex Differentiation Gene Expression Cytokine-mediated Signaling Pathway Gene Silencing By RNA Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
Pathways			Deadenylation of mRNA Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: APC GRB10 RBM12 RQCD1 SNRPB WBP11	6 interactors: AKT1 EGFR GIGYF1 GIGYF2 GRB10 MYB
Entrez ID		26058	9125
HPRD ID		11639	08828
Ensembl ID		ENSG00000204120	ENSG00000144580
Uniprot IDs		Q6Y7W6	B5MDQ4 B7Z1E5 D5MQE1 Q92600
PDB IDs			2FV2
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process MRNA 3'-end Processing RNA Processing RNA 3'-end Processing Positive Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Odontogenesis Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Metaphase/anaphase Transition Of Mitotic Cell Cycle Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Regulation Of Wnt Signaling Pathway Ribonucleoprotein Complex Biogenesis RNA Splicing Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Glucose Import Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Microtubule Polymerization Positive Regulation Of Pseudopodium Assembly Negative Regulation Of Phosphorylation Negative Regulation Of Glucose Transport Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway NcRNA Metabolic Process Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Attachment Of Spindle Microtubules To Kinetochore Histone MRNA Metabolic Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Muscle Cell Cellular Homeostasis Nuclear-transcribed MRNA Poly(A) Tail Shortening Regulation Of Microtubule Polymerization Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Odontogenesis Negative Regulation Of Microtubule Depolymerization Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Glycogen Biosynthetic Process Mitotic Spindle Assembly Checkpoint Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Spindle Assembly Checkpoint Cytoplasmic Microtubule Organization Regulation Of Glycogen Metabolic Process Negative Regulation Of Insulin Receptor Signaling Pathway Mitotic Spindle Checkpoint Termination Of RNA Polymerase II Transcription Mitotic Cytokinesis Spliceosomal SnRNP Assembly Negative Regulation Of Chromosome Segregation	Insulin-like Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Response To UV-A Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Process Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Response To Epidermal Growth Factor Stimulus Mitotic Cell Cycle Response To Epidermal Growth Factor Homeostasis Of Number Of Cells Positive Regulation Of Vasoconstriction Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Glycogen Biosynthetic Process Regulation Of Nitric-oxide Synthase Activity Regulation Of Glycogen Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Cell Cycle Process Regulation Of Vasoconstriction Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Glucose Import Cellular Response To Mechanical Stimulus Cell Cycle Regulation Of Generation Of Precursor Metabolites And Energy Cellular Response To Organonitrogen Compound Homeostatic Process Regulation Of Oxidoreductase Activity Embryonic Organ Development Gland Development In Utero Embryonic Development Positive Regulation Of Reactive Oxygen Species Metabolic Process Cell Surface Receptor Signaling Pathway Alkanesulfonate Metabolic Process Glycogen Cell Differentiation Involved In Embryonic Placenta Development Regulation Of Glucose Transport Glial Cell Development Cellular Response To Hormone Stimulus Regulation Of Glucose Metabolic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Reactive Oxygen Species Metabolic Process Embryonic Placenta Development Cell Activation Response To UV Cellular Response To Stimulus Digestive Tract Development Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling
Tagcloud ?		aberrant alter ameliorated cognitive contrary correspondingly diabetes erk1 exhibits functionally grb10 heterozygous hippocampus histopathological igf1r impairment interacting neurobehavioral neurodegeneration neuropathogenic obvious phsophorylation regulating reversed streptozotocin stz trafficking ultrastructural
Tagcloud (Difference) ?		aberrant alter ameliorated cognitive contrary correspondingly diabetes erk1 exhibits functionally grb10 heterozygous hippocampus histopathological igf1r impairment interacting neurobehavioral neurodegeneration neuropathogenic obvious phsophorylation regulating reversed streptozotocin stz trafficking ultrastructural
Tagcloud (Intersection) ?