GIGYF2 and SNRPB

Number of citations of the paper that reports this interaction (PMID 16120600)
5

Data Source:
HPRD (two hybrid)

		GIGYF2	SNRPB
Gene Name		GRB10 interacting GYF protein 2	small nuclear ribonucleoprotein polypeptides B and B1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Membrane	Nucleoplasm Spliceosomal Complex U7 SnRNP U1 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome SMN-Sm Protein Complex Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex
	Molecular Function	Poly(A) RNA Binding	Protein Binding Poly(A) RNA Binding Histone Pre-mRNA DCP Binding
	Biological Process	Feeding Behavior Adult Locomotory Behavior Post-embryonic Development Negative Regulation Of Translation Spinal Cord Motor Neuron Differentiation Mitotic G1 DNA Damage Checkpoint Multicellular Organism Growth Cellular Protein Metabolic Process Insulin-like Growth Factor Receptor Signaling Pathway Homeostasis Of Number Of Cells Within A Tissue Musculoskeletal Movement Neuromuscular Process Controlling Balance	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Histone MRNA Metabolic Process RNA Splicing Gene Expression MRNA 3'-end Processing NcRNA Metabolic Process
Pathways			mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Metabolism of non-coding RNA mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs snRNP Assembly Processing of Capped Intronless Pre-mRNA SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: APC GRB10 RBM12 RQCD1 SNRPB WBP11	48 interactors: ASCC2 BANP C14orf1 CALCOCO2 CD2BP2 CDKN2A CEP55 CLNS1A COIL CTDP1 DAB1 DDX20 DHX9 FNBP4 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GIGYF2 GOLGA2 IL7R KRT40 L3MBTL3 LSM11 LSM2 LSM8 PNMA1 PRMT5 PRMT7 PSMA3 RBPMS RFX6 SKIV2L SMN1 SMN2 SMNDC1 SNRPD1 SNRPD3 SNUPN SS18L1 STRAP STXBP2 STXBP3 TFIP11 TOP3B TRIM23 WBP4 WDR77
Entrez ID		26058	6628
HPRD ID		11639	01655
Ensembl ID		ENSG00000204120	ENSG00000125835
Uniprot IDs		Q6Y7W6	P14678 Q66K91
PDB IDs			1D3B 2Y9A 2Y9B 2Y9C 2Y9D 3CW1 3PGW
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process MRNA 3'-end Processing RNA Processing RNA 3'-end Processing Positive Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Odontogenesis Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Metaphase/anaphase Transition Of Mitotic Cell Cycle Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Regulation Of Wnt Signaling Pathway Ribonucleoprotein Complex Biogenesis RNA Splicing Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Glucose Import Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Microtubule Polymerization Positive Regulation Of Pseudopodium Assembly Negative Regulation Of Phosphorylation Negative Regulation Of Glucose Transport Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway NcRNA Metabolic Process Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Attachment Of Spindle Microtubules To Kinetochore Histone MRNA Metabolic Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Muscle Cell Cellular Homeostasis Nuclear-transcribed MRNA Poly(A) Tail Shortening Regulation Of Microtubule Polymerization Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Odontogenesis Negative Regulation Of Microtubule Depolymerization Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Glycogen Biosynthetic Process Mitotic Spindle Assembly Checkpoint Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Spindle Assembly Checkpoint Cytoplasmic Microtubule Organization Regulation Of Glycogen Metabolic Process Negative Regulation Of Insulin Receptor Signaling Pathway Mitotic Spindle Checkpoint Termination Of RNA Polymerase II Transcription Mitotic Cytokinesis Spliceosomal SnRNP Assembly Negative Regulation Of Chromosome Segregation	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Processing RNA Processing MRNA Metabolic Process Ribonucleoprotein Complex Assembly Ribonucleoprotein Complex Biogenesis Gene Expression RNA Metabolic Process Cellular Macromolecular Complex Assembly Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process NcRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Component Assembly Spliceosomal Complex Assembly Cellular Metabolic Process Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Neutrophil Degranulation Chromosome Organization Histone H4-R3 Methylation Neutrophil Activation Involved In Immune Response Peptidyl-arginine N-methylation Chromatin Organization Spliceosomal Tri-snRNP Complex Assembly Metabolic Process Histone Arginine Methylation Peptidyl-arginine Methylation Regulation Of Mitotic Cell Cycle Phase Transition Transcription, DNA-templated Neutrophil Mediated Immunity Histone MRNA Metabolic Process Chromatin Modification Neutrophil Activation Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Cellular Process RNA Biosynthetic Process Regulation Of T Cell Differentiation In Thymus Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Cell Cycle Process Pancreatic Epsilon Cell Differentiation Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration SnRNA Import Into Nucleus Spliceosomal Complex Disassembly
Tagcloud ?		aberrant alter ameliorated cognitive contrary correspondingly diabetes erk1 exhibits functionally grb10 heterozygous hippocampus histopathological igf1r impairment interacting neurobehavioral neurodegeneration neuropathogenic obvious phsophorylation regulating reversed streptozotocin stz trafficking ultrastructural
Tagcloud (Difference) ?		aberrant alter ameliorated cognitive contrary correspondingly diabetes erk1 exhibits functionally grb10 heterozygous hippocampus histopathological igf1r impairment interacting neurobehavioral neurodegeneration neuropathogenic obvious phsophorylation regulating reversed streptozotocin stz trafficking ultrastructural
Tagcloud (Intersection) ?