PPP1R16B and MISP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PPP1R16B	MISP
Description		protein phosphatase 1 regulatory subunit 16B	mitotic spindle positioning
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm	Cytoplasm Cytoskeleton Actin Filament Plasma Membrane Focal Adhesion Cell Cortex Cortical Actin Cytoskeleton Spindle Pole Centrosome Anchoring Junction Mitotic Spindle Astral Microtubule End
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Myosin Phosphatase Regulator Activity Protein Phosphatase Regulator Activity	Actin Binding Protein Binding Actin Filament Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Regulation Of Filopodium Assembly Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Establishment Of Endothelial Barrier Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Sprouting Angiogenesis	Establishment Of Mitotic Spindle Orientation Cell Migration Cell Division Organelle Localization Establishment Of Centrosome Localization Mitotic Spindle Assembly Regulation Of Protein Localization To Cell Cortex
Pathways
Drugs
Diseases
GWAS		Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis ( 28714907) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diverticular disease ( 30177863) Femur bone mineral density x serum urate levels interaction ( 34046847) Huntington's disease progression ( 28642124) Mean corpuscular volume ( 32888494) Platelet distribution width ( 32888494) Schizophrenia ( 25056061 29483656 30285260)
Interacting Genes		37 interacting genes: ATPAF2 CDCA7L CEP55 CEP70 CRX DSCAM DVL2 DVL3 FAM83A FARS2 FLYWCH1 GATA1 GFAP GOLGA2 HAPLN2 HUNK IKZF3 KCTD9 MAGOH MISP NEFL PATZ1 PHC2 PLEKHN1 RBPMS RFC5 SCNM1 SF3B4 SHC3 TACO1 TADA2A TASOR2 TFIP11 TLE5 TXN2 ZNF410 ZNF564	51 interacting genes: ACTMAP BLZF1 CCDC33 CDK1 CDPF1 CEP76 CRBN DPH2 DPPA4 EFHC2 ENKD1 FHL2 FHL5 GOLGA2 GPRASP3 HNRNPK HSF2BP HSPB2 HSPB2-C11orf52 HSPB8 IKZF3 IRAK1BP1 KRTAP12-3 LMO1 LMO2 MAP1LC3C MORN3 MORN5 OIP5 PAX6 PFDN5 PIH1D1 PIH1D2 PLK1 PNMA2 PPP1R16B PRR5L PTK2 RIBC1 RINT1 RUSC1 SNW1 SOCS7 SPATC1L SPATS1 TERF1 TRAF2 TRIB3 TRIP6 VBP1 ZNF620
Entrez ID		26051	126353
HPRD ID		15168	12695
Ensembl ID		ENSG00000101445	ENSG00000099812
Uniprot IDs		Q96T49	Q8IVT2
PDB IDs
Enriched GO Terms of Interacting Partners?			TORC1 Complex Assembly Microtubule Cytoskeleton Organization Involved In Mitosis Protein Binding R2TP Complex Mitotic G2 DNA Damage Checkpoint Signaling Golgi Disassembly Establishment Of Mitotic Spindle Orientation Prefoldin Complex Centrosome Cycle Ventricular Cardiac Muscle Cell Development Protein Kinase Binding Establishment Of Spindle Orientation Establishment Of Mitotic Spindle Localization Ubiquitin Protein Ligase Binding Box C/D SnoRNP Assembly Mitotic Nuclear Membrane Disassembly Golgi Organization Mitotic G2/M Transition Checkpoint Cytoplasm Nucleus Establishment Of Spindle Localization
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