OSBPL3 and ZNF497

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		OSBPL3	ZNF497
Description		oxysterol binding protein like 3	zinc finger protein 497
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Nuclear Membrane Filopodium Tip Cell Projection Perinuclear Endoplasmic Reticulum	Nucleus
	Molecular Function	Protein Binding Lipid Binding Cholesterol Binding Sterol Transfer Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Bile Acid Biosynthetic Process Lipid Transport Sterol Transport	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways		Synthesis of bile acids and bile salts
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Heel bone mineral density x serum urate levels interaction ( 34046847) Pursuit maintenance gain ( 29064472) Sulfasalazine-induced agranulocytosis ( 28762467)
Interacting Genes		26 interacting genes: ACSM1 BYSL CRYAA FAM161A GABARAPL1 GABARAPL2 LNX1 MCRS1 PLK4 PRPF18 PRPF3 RALGPS2 RPL11 STK35 SYTL4 TCEA2 TCEANC TRAF3IP3 WT1 YWHAB YWHAG ZBTB16 ZNF48 ZNF497 ZNF648 ZNF835	39 interacting genes: CCDC136 CYSRT1 DVL3 GGA3 GOLGA6L9 HOOK2 KHDRBS2 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP4-12 KRTAP4-4 KRTAP6-3 KRTAP9-3 MCC MDFI MID2 MTUS2 NBPF19 NOTCH2NLA OSBPL3 PICK1 PTPN21 PURB SULT2B1 TNS2 TRIM41 VWC2 ZBTB8A ZNF473 ZNF526 ZNF71 ZNF792 ZNF835 ZNF837 ZRANB1
Entrez ID		26031	162968
HPRD ID		09474	15806
Ensembl ID		ENSG00000070882	ENSG00000174586
Uniprot IDs		Q9H4L5	Q6ZNH5
PDB IDs		7CYZ 7DEI 7DEJ
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Localization To Nucleolus Cellular Response To Nitrogen Starvation	Intermediate Filament Keratin Filament
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