OSBPL3 and TRAF3IP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		OSBPL3	TRAF3IP3
Description		oxysterol binding protein like 3	TRAF3 interacting protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Nuclear Membrane Filopodium Tip Cell Projection Perinuclear Endoplasmic Reticulum	Golgi Membrane Mitochondrion Mitochondrial Outer Membrane Lysosome Lysosomal Membrane Golgi Apparatus Plasma Membrane Membrane
	Molecular Function	Protein Binding Lipid Binding Cholesterol Binding Sterol Transfer Activity	Protein Binding Protein-macromolecule Adaptor Activity Molecular Adaptor Activity
	Biological Process	Bile Acid Biosynthetic Process Lipid Transport Sterol Transport	Cytoplasmic Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Type I Interferon Production
Pathways		Synthesis of bile acids and bile salts
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Heel bone mineral density x serum urate levels interaction ( 34046847) Pursuit maintenance gain ( 29064472) Sulfasalazine-induced agranulocytosis ( 28762467)	Alopecia areata ( 25608926) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Orofacial clefts ( 33137956) Red blood cell count ( 27863252 32888494) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		26 interacting genes: ACSM1 BYSL CRYAA FAM161A GABARAPL1 GABARAPL2 LNX1 MCRS1 PLK4 PRPF18 PRPF3 RALGPS2 RPL11 STK35 SYTL4 TCEA2 TCEANC TRAF3IP3 WT1 YWHAB YWHAG ZBTB16 ZNF48 ZNF497 ZNF648 ZNF835	47 interacting genes: ATG16L1 CBARP CCDC136 CCDC138 CCDC88B CCNC CDCA7L CEP68 CEP70 COQ9 CPLX4 CREB3L3 EBAG9 EMD EVI2B FAM209A FATE1 GOLGA6L9 GOLM2 GORAB GRAMD2A KASH5 KIR2DL3 KRT27 L3MBTL3 LIME1 LRRC25 MFF MINAR1 NDEL1 OSBPL3 PLEKHO1 PSTPIP1 RACGAP1 RIC3 RILPL1 SP100 STMN4 STX1A STX4 TFIP11 TMEM139 TRAF3 TRIM36 WAC ZNRD2 ZRANB1
Entrez ID		26031	80342
HPRD ID		09474	16305
Ensembl ID		ENSG00000070882	ENSG00000009790
Uniprot IDs		Q9H4L5	B1AJU2 B3KWQ9 E2QRE5 Q9Y228
PDB IDs		7CYZ 7DEI 7DEJ
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Localization To Nucleolus Cellular Response To Nitrogen Starvation	Identical Protein Binding Organelle Organization
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