LRP10 and ST6GALNAC6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LRP10	ST6GALNAC6
Description		LDL receptor related protein 10	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Clathrin-coated Pit Membrane	Golgi Membrane Cytoplasm Golgi Apparatus Plasma Membrane Membrane
	Molecular Function	Low-density Lipoprotein Particle Receptor Activity Protein Binding	Alpha-N-acetylgalactosaminide Alpha-2,6-sialyltransferase Activity Protein Binding Sialyltransferase Activity Transferase Activity Glycosyltransferase Activity
	Biological Process	Lipid Metabolic Process Lipid Transport Endocytosis Vesicle-mediated Transport Inner Ear Development	Ganglioside Biosynthetic Process Protein Glycosylation Lipid Metabolic Process Ceramide Metabolic Process Glycosylceramide Metabolic Process Glycosphingolipid Metabolic Process Glycosphingolipid Biosynthetic Process Glycoprotein Metabolic Process Oligosaccharide Metabolic Process Oligosaccharide Biosynthetic Process Cell-cell Recognition
Pathways		Retinoid metabolism and transport	Sialic acid metabolism Lewis blood group biosynthesis Glycosphingolipid biosynthesis
Drugs
Diseases
GWAS		Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) Neutrophil count ( 32888494)	Blood protein levels ( 30072576) Body mass index ( 26426971)
Interacting Genes		23 interacting genes: C16orf92 CISD2 EBP FAM209A GGA3 GJB5 GOLM2 GORAB HTRA1 LMNA MGST3 MRPS18B NOTO PDCD1LG2 PLEKHO1 SLC10A1 SLC14A2 SLC71A2 SMIM1 ST6GALNAC6 TMEM179B TMEM237 TMEM243	5 interacting genes: ANKRD46 APP ATXN1 ATXN1L LRP10
Entrez ID		26020	30815
HPRD ID		14311	18111
Ensembl ID		ENSG00000197324	ENSG00000160408
Uniprot IDs		Q7Z4F1	A0A0S2Z5G9 B4DU80 F6SGE3 Q969X2
PDB IDs
Enriched GO Terms of Interacting Partners?			POZ Domain Binding Memory Learning Learning Or Memory Cognition Visual Learning Social Behavior Lung Alveolus Development Visual Behavior Clathrin-coated Pit Amyloid-beta Complex Growth Cone Lamellipodium Adult Locomotory Behavior Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Chromatin Binding Associative Learning Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Adult Behavior Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Locomotory Behavior Nervous System Process Regulation Of Spontaneous Synaptic Transmission Postsynapse Negative Regulation Of Transcription By RNA Polymerase II NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Brain Development
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