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CENPF and CHMP2B
Number of citations of the paper that reports this interaction (PubMedID
16730941
)
0
Data Source:
HPRD
(two hybrid)
CENPF
CHMP2B
Description
centromere protein F
charged multivesicular body protein 2B
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Kinetochore
Chromatin
Spindle Pole
Outer Kinetochore
Nucleus
Nuclear Envelope
Nucleoplasm
Chromosome
Cytoplasm
Centrosome
Spindle
Cytosol
Cytoskeleton
Axoneme
Nuclear Matrix
Midbody
Ciliary Basal Body
Pronucleus
Perinuclear Region Of Cytoplasm
Ciliary Transition Fiber
Autophagosome Membrane
Kinetochore
ESCRT III Complex
Nuclear Pore
Cytoplasm
Lysosome
Lysosomal Membrane
Endosome
Late Endosome
Multivesicular Body
Kinetochore Microtubule
Cytosol
Plasma Membrane
Postsynaptic Density
Membrane
Midbody
Late Endosome Membrane
Multivesicular Body Membrane
Extracellular Exosome
Glutamatergic Synapse
Amphisome Membrane
Molecular Function
Chromatin Binding
Protein Binding
Microtubule Binding
Protein Homodimerization Activity
Dynein Complex Binding
DNA-binding Transcription Factor Binding
Protein Binding
Protein Domain Specific Binding
Cadherin Binding
Biological Process
Mitotic Cell Cycle
Kidney Development
Chromosome Segregation
Mitotic Spindle Assembly Checkpoint Signaling
Muscle Organ Development
Response To Xenobiotic Stimulus
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Protein Transport
Regulation Of Striated Muscle Tissue Development
Ventricular System Development
Cell Differentiation
Negative Regulation Of DNA-templated Transcription
Cell Division
Metaphase Chromosome Alignment
Kinetochore Assembly
DNA Biosynthetic Process
Plasma Membrane Repair
Autophagy
Nucleus Organization
Endosome Organization
Vacuolar Transport
Mitotic Metaphase Chromosome Alignment
Regulation Of Centrosome Duplication
Protein Transport
Macroautophagy
Viral Release From Host Cell
Nuclear Membrane Reassembly
Endosome Transport Via Multivesicular Body Sorting Pathway
Multivesicular Body Assembly
Viral Budding Via Host ESCRT Complex
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Late Endosome To Vacuole Transport
Viral Budding From Plasma Membrane
Modulation Of Chemical Synaptic Transmission
Cognition
Vesicle Fusion With Vacuole
Multivesicular Body-lysosome Fusion
Midbody Abscission
Neuron Cellular Homeostasis
Multivesicular Body Sorting Pathway
Membrane Fission
Autophagosome Maturation
Regulation Of Modification Of Postsynaptic Structure
Regulation Of Postsynapse Organization
Regulation Of Mitotic Spindle Assembly
Late Endosome To Lysosome Transport
ESCRT III Complex Disassembly
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Polo-like kinase mediated events
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Budding and maturation of HIV virion
Macroautophagy
Pyroptosis
Endosomal Sorting Complex Required For Transport (ESCRT)
HCMV Late Events
Late endosomal microautophagy
Sealing of the nuclear envelope (NE) by ESCRT-III
Translation of Replicase and Assembly of the Replication Transcription Complex
Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
Frontotemporal lobar degeneration (FTLD), including: Pick disease of brain; Frontotemporal dementia (FTD); Ubiquitin-positive frontotemporal dementia (UP-FTD); Progressive supranuclear palsy type 1 (PSNP1); Inclusion body myopathy with early-onset paget disease and frontotemporal dementia (IBMPFD); Frontotemporal dementia, chromosome 3-linked (FTD3)
GWAS
Age-related cognitive decline (memory) (slope of z-scores) (
30954325
)
Lung function (FVC) (
30061609
)
Response to antineoplastic agents (
21659360
)
Serum immune biomarker levels (
32066700
)
Tourette's syndrome or obsessive-compulsive disorder (
25158072
)
Interacting Genes
12 interacting genes:
BRAP
CDK1
CENPE
CHMP2B
FNTA
FNTB
KPNA1
NDEL1
NUP133
SNAP25
SVIL
TOP3B
14 interacting genes:
ATP5F1C
CENPF
CFTR
CHMP3
DPY30
FBXO7
MALSU1
PHGDH
PNMA1
SNCA
TERF2IP
TRAF2
USP54
USP8
Entrez ID
1063
25978
HPRD ID
02582
13174
Ensembl ID
ENSG00000117724
ENSG00000083937
Uniprot IDs
A0A9L9PXU7
P49454
A0A087WW88
B2RE76
Q9UQN3
PDB IDs
2JQK
Enriched GO Terms of Interacting Partners
?
Protein Farnesyltransferase Activity
Protein Farnesyltransferase Complex
Protein Farnesylation
Microtubule Associated Complex
Protein Prenyltransferase Activity
Kinetochore
Midbody
Protein Prenylation
Prenyltransferase Activity
Acetyltransferase Activator Activity
Chromosome Localization
Nuclear Pore
Nucleus Organization
Kinetochore Microtubule
Nuclear Localization Sequence Binding
Nuclear Envelope Organization
Microtubule Cytoskeleton Organization Involved In Mitosis
Organelle Fusion
Chromosome Organization
Chromosome Segregation
Cytosol
Organelle Organization
Pronuclear Fusion
Chromosome, Centromeric Region
Microtubule Plus-end Directed Mitotic Chromosome Migration
Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore
Mitotic Metaphase Chromosome Alignment
Peptide Pheromone Maturation
Alpha-tubulin Binding
Cortisol Dehydrogenase (NADP+) Activity
11-beta-hydroxysteroid Dehydrogenase (NADP+) Activity
7-beta-hydroxysteroid Dehydrogenase (NADP+) Activity
Glutamatergic Postsynaptic Density
Negative Regulation Of Zinc Ion Transmembrane Import
RNA Topoisomerase Activity
Nuclear Membrane Organization
Organelle Localization
Regulation Of Microtubule-based Movement
Regulation Of Cellular Localization
Mitotic DNA-templated DNA Replication
Spindle
Cyclin B1-CDK1 Complex
Regulation Of Protein Localization
Cyclin A1-CDK1 Complex
Cyclin A2-CDK1 Complex
Metaphase Chromosome Alignment
CAAX-protein Geranylgeranyltransferase Activity
CAAX-protein Geranylgeranyltransferase Complex
Hydroxylysine Biosynthetic Process
Detoxification Of Zinc Ion
Organelle Localization
Midbody
Dynein Complex Binding
Regulation Of Exocytosis
Intracellularly ATP-gated Chloride Channel Activity
Positive Regulation Of Voltage-gated Chloride Channel Activity
Sec61 Translocon Complex Binding
Response To Desipramine
Negative Regulation Of Norepinephrine Uptake
Phospholipase D Inhibitor Activity
Positive Regulation Of SNARE Complex Assembly
Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission
TORC2 Complex Disassembly
K63-linked Deubiquitinase Activity
Glial Cytoplasmic Inclusion
Classical Lewy Body
Lewy Body Corona
Lewy Neurite
Phosphoglycerate Dehydrogenase Activity
Negative Regulation Of Mitochondrial Translation
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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