CENPF and NUP133

Number of citations of the paper that reports this interaction (PMID 17363900)
51

Data Source:
HPRD (in vivo, two hybrid)

		CENPF	NUP133
Gene Name		centromere protein F, 350/400kDa	nucleoporin 133kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Chromatin Spindle Pole Condensed Chromosome Outer Kinetochore Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Spindle Cytosol Nuclear Matrix Midbody Pronucleus Perinuclear Region Of Cytoplasm	Condensed Chromosome Kinetochore Condensed Chromosome Outer Kinetochore Nuclear Envelope Nuclear Pore Cytosol Membrane Nuclear Pore Outer Ring Nuclear Membrane
	Molecular Function	Chromatin Binding Protein Binding Protein C-terminus Binding Transcription Factor Binding Protein Homodimerization Activity Dynein Binding	Nucleocytoplasmic Transporter Activity Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Mitotic Spindle Assembly Checkpoint Muscle Organ Development Cell Proliferation Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Regulation Of Striated Muscle Tissue Development Cell Differentiation Response To Drug Negative Regulation Of Transcription, DNA-templated Cell Division Metaphase Plate Congression Kinetochore Assembly Regulation Of Cell Cycle DNA Biosynthetic Process	Mitotic Cell Cycle Carbohydrate Metabolic Process MRNA Export From Nucleus Nuclear Pore Organization Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Paraxial Mesoderm Development Transmembrane Transport
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion G2/M Transition Mitotic Anaphase Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Polo-like kinase mediated events Cell Cycle, Mitotic M Phase	Mitotic Prometaphase Separation of Sister Chromatids Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown Mitotic Anaphase SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Resolution of Sister Chromatid Cohesion Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS		Response to antineoplastic agents ( 21659360)
Protein-Protein Interactions		10 interactors: BRAP CENPE CHMP2B FNTA FNTB NDEL1 NUP133 SNAP25 SVIL TOP3B	3 interactors: CENPF NUP107 NUP98
Entrez ID		1063	55746
HPRD ID		02582	06354
Ensembl ID		ENSG00000117724	ENSG00000069248
Uniprot IDs		P49454	Q8WUM0
PDB IDs			1XKS 3CQC 3CQG 3I4R
Enriched GO Terms of Interacting Partners?		Establishment Of Chromosome Localization Protein Farnesylation Chromosome Segregation Establishment Of Organelle Localization Nucleus Organization Protein Prenylation Organelle Localization Regulation Of Cell Cycle Regulation Of Rhodopsin Mediated Signaling Pathway Mitotic Metaphase Plate Congression Organelle Organization Rhodopsin Mediated Signaling Pathway Metaphase Plate Congression Nuclear Envelope Disassembly Mitotic Cell Cycle Process Regulation Of Cell Division Mitotic Cell Cycle Positive Regulation Of Cell Cycle Mitotic Nuclear Division Membrane Organization Nuclear Envelope Organization Cellular Protein Complex Assembly Positive Regulation Of Tubulin Deacetylation Phototransduction, Visible Light Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Cell Cycle Process Detection Of Visible Light Cellular Response To Light Stimulus Phototransduction Establishment Of Localization In Cell Detection Of Light Stimulus Regulation Of Cell Cycle Process Regulation Of Mitotic Nuclear Division Mitotic Chromosome Movement Towards Spindle Pole Cellular Response To Radiation Cell Cycle Wound Healing Cellular Localization Cellular Macromolecular Complex Assembly Regulation Of Tubulin Deacetylation Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Detection Of Abiotic Stimulus Positive Regulation Of Axon Regeneration Positive Regulation Of Deacetylase Activity Response To Wounding Retrograde Axon Cargo Transport Viral Budding Via Host ESCRT Complex Viral Life Cycle	Nuclear Pore Complex Assembly Nuclear Pore Organization Pore Complex Assembly Cellular Protein Complex Assembly Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Cellular Macromolecular Complex Assembly Nuclear Envelope Organization Mitotic Cell Cycle Process Glucose Transport Hexose Transport Mitotic Cell Cycle Viral Transcription Regulation Of Glucose Transport MRNA Transport Nucleus Organization Carbohydrate Transport Protein Complex Assembly Cell Cycle Process RNA Transport RNA Localization Cell Cycle Viral Life Cycle Protein Transport Pathogenesis Protein Import Into Nucleus, Docking Establishment Of Protein Localization Nucleocytoplasmic Transport Nuclear Transport Cellular Component Assembly Protein Localization Establishment Of Localization In Cell Endomembrane System Organization Cytokine-mediated Signaling Pathway Cellular Localization Viral Process Cellular Response To Cytokine Stimulus Organelle Organization Cytoplasmic Transport Response To Cytokine Kinetochore Assembly Kinetochore Organization Membrane Organization Macromolecule Biosynthetic Process Metaphase Plate Congression Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Establishment Of Chromosome Localization
Tagcloud ?		assembled causal computational coordinated cross drivers engineered foxm1 genetically genome indicator interactomes interrogation malignancy master networks profiles promote prostate regulators regulatory represents robust shows synergistic synergistically validation valuable wide	anchored anchoring asun asunder bicaudal bicd2 cenp centromere centrosome coimmunoprecipitation conservation coupling dynein flies g2 germline lis1 lissencephaly meiosis motors multinucleation perinuclear pore prophase ranbp2 rescues spermatocytes spindles uncoupling
Tagcloud (Difference) ?		assembled causal computational coordinated cross drivers engineered foxm1 genetically genome indicator interactomes interrogation malignancy master networks profiles promote prostate regulators regulatory represents robust shows synergistic synergistically validation valuable wide	anchored anchoring asun asunder bicaudal bicd2 cenp centromere centrosome coimmunoprecipitation conservation coupling dynein flies g2 germline lis1 lissencephaly meiosis motors multinucleation perinuclear pore prophase ranbp2 rescues spermatocytes spindles uncoupling
Tagcloud (Intersection) ?