NECAP1 and SNAP91

Number of citations of the paper that reports this interaction (PMID 17762867)
8

Data Source:
HPRD (in vivo)

		NECAP1	SNAP91
Gene Name		NECAP endocytosis associated 1	synaptosomal-associated protein, 91kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Coated Pit Clathrin Vesicle Coat	Plasma Membrane Coated Pit Clathrin-coated Vesicle
	Molecular Function		Protein Binding 1-phosphatidylinositol Binding Protein Kinase Binding Clathrin Binding
	Biological Process	Endocytosis Protein Transport	Synaptic Transmission Protein Transport Clathrin Coat Assembly Regulation Of Clathrin-mediated Endocytosis
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS			Bipolar disorder (mood-incongruent) ( 23092984)
Protein-Protein Interactions		6 interactors: AMPH APP DAB2 HIP1 REL SNAP91	8 interactors: AP2A2 AP2B1 EPS15 NECAP1 OGT PLCG1 TRAF3IP1 TUBA1B
Entrez ID		25977	9892
HPRD ID		14819	06391
Ensembl ID		ENSG00000089818	ENSG00000065609
Uniprot IDs		Q8NC96	B7Z2N2 O60641
PDB IDs
Enriched GO Terms of Interacting Partners?		Clathrin Coat Assembly Membrane Budding Regulation Of Clathrin-mediated Endocytosis Vesicle-mediated Transport Endocytosis Regulation Of Endocytosis Vesicle Organization Positive Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Proteolysis Cellular Protein Complex Assembly Regulation Of Vesicle-mediated Transport Positive Regulation Of Protein Metabolic Process Signaling Cell Communication Positive Regulation Of Endocytosis Cellular Macromolecular Complex Assembly Regulation Of Proteolysis Leading Edge Cell Differentiation Synaptic Growth At Neuromuscular Junction Learning Cellular Component Assembly Regulation Of Protein Binding Positive Regulation Of Peptidase Activity Collateral Sprouting In Absence Of Injury Positive Regulation Of Clathrin-mediated Endocytosis Membrane Organization Regulation Of Protein Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Early Endosome To Late Endosome Transport Apoptotic Process Programmed Cell Death Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Protein Complex Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Death Death Axon Choice Point Recognition Regulation Of Binding Positive Regulation Of Cellular Metabolic Process Learning Or Memory Positive Regulation Of Integrin-mediated Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Transport Cognition Neuron Remodeling Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Positive Regulation Of Non-canonical Wnt Signaling Pathway Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Early Endosome To Late Endosome Transport	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Endocytosis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Defense Response To Virus Regulation Of Immune System Process Regulation Of Defense Response To Virus By Virus Vesicle-mediated Transport Neurotrophin TRK Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neurotrophin Signaling Pathway Intracellular Transport Regulation Of Signal Transduction Clathrin-mediated Endocytosis Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Signaling Transport Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Organic Substance Establishment Of Localization In Cell Axon Guidance Cell Morphogenesis Negative Regulation Of Signal Transduction Cell Projection Organization Negative Regulation Of Signaling Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Cellular Localization Ephrin Receptor Signaling Pathway Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Axonogenesis Response To Organic Substance Viral Process Protein Transport Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Establishment Of Protein Localization Chemotaxis Response To Growth Factor Movement Of Cell Or Subcellular Component Cytoskeleton-dependent Intracellular Transport Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Response To External Stimulus
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