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NECAP1 and DAB2
Number of citations of the paper that reports this interaction (PubMedID
17762867
)
67
Data Source:
HPRD
(in vivo)
NECAP1
DAB2
Description
NECAP endocytosis associated 1
DAB adaptor protein 2
Image
GO Annotations
Cellular Component
Cytosol
Plasma Membrane
Clathrin-coated Pit
Membrane
Clathrin Vesicle Coat
Clathrin-coated Vesicle Membrane
Cytoplasmic Vesicle
Presynapse
Fibrillar Center
Cytoplasm
Lysosomal Membrane
Cytosol
Plasma Membrane
Clathrin-coated Pit
Focal Adhesion
Membrane
Clathrin-coated Vesicle
Clathrin-coated Vesicle Membrane
Cytoplasmic Vesicle
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Protein Binding
Clathrin Adaptor Activity
Cargo Receptor Activity
SMAD Binding
Low-density Lipoprotein Particle Receptor Binding
Biological Process
Endocytosis
Protein Transport
Vesicle-mediated Transport
Presynaptic Endocytosis
Negative Regulation Of Transcription By RNA Polymerase II
Endocytosis
Receptor-mediated Endocytosis
Apoptotic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Integrin-mediated Signaling Pathway
Positive Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Neuron Projection Development
Protein Transport
Wnt Signaling Pathway
Cell Differentiation
Negative Regulation Of Cell Growth
Positive Regulation Of Cell Migration
Positive Regulation Of Aldosterone Biosynthetic Process
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Leading Edge Cell Differentiation
Negative Regulation Of Apoptotic Process
Positive Regulation Of Endocytosis
Positive Regulation Of Transcription By RNA Polymerase II
Clathrin Coat Assembly
Response To Steroid Hormone
Negative Regulation Of Epithelial Cell Proliferation
Positive Regulation Of SMAD Protein Signal Transduction
Negative Regulation Of Androgen Receptor Signaling Pathway
Negative Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Transforming Growth Factor Beta Stimulus
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Response To Salt
Negative Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Positive Regulation Of Clathrin-dependent Endocytosis
Positive Regulation Of Early Endosome To Late Endosome Transport
Positive Regulation Of Aldosterone Secretion
Pathways
Golgi Associated Vesicle Biogenesis
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Gap junction degradation
Formation of annular gap junctions
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Drugs
Diseases
GWAS
Albumin-globulin ratio (
29403010
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Apolipoprotein A1 levels (
32203549
)
Appendicular lean mass (
33097823
)
Aspartate aminotransferase levels (
33547301
29403010
)
Birth weight (
31043758
)
Chronic kidney disease (
20383146
31152163
)
Creatinine levels (
31015462
)
Diverticular disease (
30177863
)
Estimated glomerular filtration rate (
31451708
31152163
30604766
31015462
)
Estimated glomerular filtration rate in diabetes (
31451708
)
Estimated glomerular filtration rate in non-diabetics (
31451708
)
Glomerular filtration rate (creatinine) (
28452372
26831199
)
Glomerular filtration rate in non diabetics (creatinine) (
26831199
)
HDL cholesterol levels (
32203549
)
Health literacy (
31250787
)
Heel bone mineral density (
30598549
28869591
)
Height (
31562340
)
Non-albumin protein levels (
29403010
)
Pancreatic cancer (
22158540
)
Premature menopause in childhood cancer survivors (
29432556
)
Self-reported allergy (
23817569
)
Systemic lupus erythematosus (
19838195
)
Urate levels (
23263486
)
Waist-hip ratio (
28552196
)
Interacting Genes
10 interacting genes:
AMPH
AP1B1
APP
DAB2
DAPK1
DNAJC5
HIP1
REL
SNAP91
SNCA
40 interacting genes:
AP2M1
APLP1
APLP2
APP
ATXN1L
AXIN1
CDC16
CDK1
CSK
DAB2IP
DIP2A
DVL1
DVL3
FCHO1
FCHO2
FGR
GRB2
INPP5D
ITGB3
ITGB5
ITSN1
LDLR
LRP1
LRP2
LRP8
MIB1
MYO6
NECAP1
PIN1
PRKCB
PRKCD
PRKCG
SGIP1
SMAD2
SMAD3
SMURF2
SRC
SUMO2
TGFBR1
TGFBR2
Entrez ID
25977
1601
HPRD ID
14819
03139
Ensembl ID
ENSG00000089818
ENSG00000153071
Uniprot IDs
Q8NC96
B2RAW0
P98082
PDB IDs
6RH5
6RH6
2LSW
6O5O
6OVF
Enriched GO Terms of Interacting Partners
?
Synaptic Vesicle
Vesicle-mediated Transport
Endocytosis
Regulation Of Vesicle-mediated Transport
Clathrin Coat Assembly
Phospholipid Binding
Import Into Cell
Regulation Of Receptor-mediated Endocytosis
Regulation Of Endocytosis
Clathrin Binding
Clathrin-coated Vesicle Membrane
Positive Regulation Of Endocytosis
Cytoplasmic Vesicle
Apoptotic Process
Positive Regulation Of Receptor-mediated Endocytosis
Programmed Cell Death
Cell Death
Regulation Of Transport
Presynapse
Clathrin-coated Pit
Clathrin-coated Vesicle
Vesicle-mediated Transport In Synapse
Clathrin Adaptor Activity
Regulation Of Clathrin-dependent Endocytosis
Regulation Of Apoptotic Process
Synaptic Vesicle Membrane
Regulation Of Neurotransmitter Uptake
Regulation Of Programmed Cell Death
Cellular Response To Copper Ion
Regulation Of Presynapse Organization
Regulation Of Long-term Neuronal Synaptic Plasticity
Low-density Lipoprotein Particle Receptor Binding
Regulation Of Presynapse Assembly
Positive Regulation Of Small Molecule Metabolic Process
Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Receptor-mediated Endocytosis
Amyloid Fibril Formation
Microglial Cell Activation
Leukocyte Activation Involved In Inflammatory Response
Synaptic Vesicle Exocytosis
Response To Copper Ion
Response To Cytokine
Positive Regulation Of Catabolic Process
Response To Peptide
Synaptic Vesicle Endocytosis
Postsynapse
Presynaptic Endocytosis
Regulation Of Neuron Apoptotic Process
Protein-containing Complex Assembly
Actin Cytoskeleton
Clathrin-coated Pit
Endocytosis
Import Into Cell
Plasma Membrane
Cell Surface Receptor Signaling Pathway
Anatomical Structure Morphogenesis
Receptor Complex
Signal Transduction
Regulation Of Endocytosis
Regulation Of Vesicle-mediated Transport
Receptor-mediated Endocytosis
Vesicle-mediated Transport
Regulation Of Cellular Component Organization
Intracellular Signal Transduction
Regulation Of Protein Catabolic Process
Regulation Of Signaling
Positive Regulation Of Multicellular Organismal Process
Positive Regulation Of Cellular Component Organization
Positive Regulation Of Developmental Process
Response To Growth Factor
Regulation Of Cell Communication
Clathrin-dependent Endocytosis
Regulation Of Multicellular Organismal Process
Regulation Of Developmental Process
Cellular Response To Growth Factor Stimulus
Regulation Of Protein Metabolic Process
Regulation Of Signal Transduction
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Tube Morphogenesis
Positive Regulation Of Protein Catabolic Process
Regulation Of Transport
Low-density Lipoprotein Particle Receptor Activity
Membrane
I-SMAD Binding
Cellular Response To Oxygen-containing Compound
Presynaptic Endocytosis
Regulation Of Cellular Response To Growth Factor Stimulus
Vesicle-mediated Transport In Synapse
Regulation Of Protein Localization
Immune Response-activating Cell Surface Receptor Signaling Pathway
SMAD Binding
Cytosol
Positive Regulation Of Lysosomal Protein Catabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Neuron Projection Morphogenesis
Enzyme-linked Receptor Protein Signaling Pathway
Anatomical Structure Formation Involved In Morphogenesis
Cell Projection Morphogenesis
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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