NECAP1 and AMPH

Number of citations of the paper that reports this interaction (PMID 17762867)
8

Data Source:
HPRD (in vitro, in vivo)

		NECAP1	AMPH
Gene Name		NECAP endocytosis associated 1	amphiphysin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Coated Pit Clathrin Vesicle Coat	Synaptic Vesicle Actin Cytoskeleton Cell Junction Synaptic Vesicle Membrane Leading Edge Membrane
	Molecular Function		Protein Binding Phospholipid Binding
	Biological Process	Endocytosis Protein Transport	Endocytosis Synaptic Transmission Learning Synaptic Vesicle Endocytosis
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: AMPH APP DAB2 HIP1 REL SNAP91	27 interactors: AP1B1 AP2A1 AP2A2 ARL16 BIN1 CABIN1 CCDC67 CDK1 CDK5 CDK5R1 CLTC DNM1 DNM2 DYRK1A ITSN2 KHDRBS1 MAPK6 NECAP1 PLD2 PPP3CC SH3GL2 SH3GLB1 SYN1 SYNJ1 TERF1 UBC VTN
Entrez ID		25977	273
HPRD ID		14819	02687
Ensembl ID		ENSG00000089818	ENSG00000078053
Uniprot IDs		Q8NC96	P49418
PDB IDs			1KY7 1UTC 3SOG 4ATM
Enriched GO Terms of Interacting Partners?		Clathrin Coat Assembly Membrane Budding Regulation Of Clathrin-mediated Endocytosis Vesicle-mediated Transport Endocytosis Regulation Of Endocytosis Vesicle Organization Positive Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Proteolysis Cellular Protein Complex Assembly Regulation Of Vesicle-mediated Transport Positive Regulation Of Protein Metabolic Process Signaling Cell Communication Positive Regulation Of Endocytosis Cellular Macromolecular Complex Assembly Regulation Of Proteolysis Leading Edge Cell Differentiation Synaptic Growth At Neuromuscular Junction Learning Cellular Component Assembly Regulation Of Protein Binding Positive Regulation Of Peptidase Activity Collateral Sprouting In Absence Of Injury Positive Regulation Of Clathrin-mediated Endocytosis Membrane Organization Regulation Of Protein Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Early Endosome To Late Endosome Transport Apoptotic Process Programmed Cell Death Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Protein Complex Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Death Death Axon Choice Point Recognition Regulation Of Binding Positive Regulation Of Cellular Metabolic Process Learning Or Memory Positive Regulation Of Integrin-mediated Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Transport Cognition Neuron Remodeling Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Positive Regulation Of Non-canonical Wnt Signaling Pathway Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Early Endosome To Late Endosome Transport	Endocytosis Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Receptor Metabolic Process Post-Golgi Vesicle-mediated Transport Synaptic Vesicle Recycling Receptor-mediated Endocytosis Synaptic Vesicle Transport Receptor Internalization Regulation Of Signaling Synaptic Transmission Axon Guidance Peptidyl-threonine Phosphorylation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of ERBB Signaling Pathway Neuron Projection Morphogenesis Positive Regulation Of Transport Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Axonogenesis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Neuron Projection Development Axon Development Regulation Of Signal Transduction Cell Projection Morphogenesis Establishment Of Vesicle Localization Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Defense Response To Virus By Virus Positive Regulation Of Apoptotic Process Regulation Of Vesicle-mediated Transport Positive Regulation Of Programmed Cell Death Cell Part Morphogenesis Chemotaxis Vesicle Localization Regulation Of Cellular Component Organization Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Hyaluronan Biosynthetic Process Cellular Localization Positive Regulation Of Cell Death Ephrin Receptor Signaling Pathway Regulation Of Cell Cycle Arrest Neurotrophin Signaling Pathway Establishment Of Localization In Cell
Tagcloud ?			10a 10as 6b 6br 7h amphetamine antipsychotic butan cataleptogenic demonstrable dimethoxy headtwitch hexahydro histaminergic ht2a ht2c hydrochloride hyperlocomotion id50 iodoamphetamine mesocortical mesolimbic microdialysis neurotransmission pyrido pyrrolo quinoxalin sert unwanted
Tagcloud (Difference) ?			10a 10as 6b 6br 7h amphetamine antipsychotic butan cataleptogenic demonstrable dimethoxy headtwitch hexahydro histaminergic ht2a ht2c hydrochloride hyperlocomotion id50 iodoamphetamine mesocortical mesolimbic microdialysis neurotransmission pyrido pyrrolo quinoxalin sert unwanted
Tagcloud (Intersection) ?