TAS2R19 and TMEM167B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TAS2R19	TMEM167B
Description		taste 2 receptor member 19	transmembrane protein 167B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Bitter Taste Receptor Activity	Protein Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Signal Transduction G Protein-coupled Receptor Signaling Pathway Sensory Perception Of Taste	Constitutive Secretory Pathway
Pathways		G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors)
Drugs
Diseases
GWAS			Apolipoprotein B levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		7 interacting genes: LNPEP MMGT1 PGRMC2 PVR TMEM14B TMEM167B TYW1B	33 interacting genes: ACKR2 AGPAT3 APOL3 AQP10 AQP6 ASPH C14orf180 CD300C CD47 CTXN3 EBP FXYD6-FXYD2 HSD17B11 HSD17B13 LETMD1 LSS MGST2 PLLP REEP4 SACM1L SEC22B SERINC2 SLC34A3 SLC71A2 SMPD2 STX12 STX1B TAS2R19 TM4SF19 TMEM100 TMEM107 UNC50 ZDHHC21
Entrez ID		259294	56900
HPRD ID		18156	16474
Ensembl ID		ENSG00000212124	ENSG00000215717
Uniprot IDs		P59542	A0A494C0V7 Q9NRX6
PDB IDs
Enriched GO Terms of Interacting Partners?		Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Iron Ion Transport TRNA-4-demethylwyosine Synthase Activity Susceptibility To T Cell Mediated Cytotoxicity Cobalt Ion Transmembrane Transporter Activity Early Endosome Lumen Neuropeptide Catabolic Process Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Susceptibility To Natural Killer Cell Mediated Cytotoxicity Heme Transmembrane Transporter Activity Heme Transport Constitutive Secretory Pathway Inorganic Cation Transmembrane Transporter Activity Ferrous Iron Transmembrane Transporter Activity Wybutosine Biosynthetic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence EMC Complex Cobalt Ion Transport	Membrane Endoplasmic Reticulum Steroid Dehydrogenase Activity Lipid Droplet SNAP Receptor Activity Lipid Metabolic Process Water Channel Activity Lipid Biosynthetic Process Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity
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