COG4 and COG1

Number of citations: 48 (PubMedID 11980916)
Data Source: HPRD (in vivo, in vitro)

		COG4	COG1
Name		component of oligomeric golgi complex 4	component of oligomeric golgi complex 1
Structure			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Membrane Golgi Transport Complex Trans-Golgi Network Membrane	Golgi Membrane Golgi Apparatus Membrane Golgi Transport Complex Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Retrograde Transport, Vesicle Recycling Within Golgi Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Protein Transport Glycosylation	Retrograde Transport, Vesicle Recycling Within Golgi Intra-Golgi Vesicle-mediated Transport Golgi Organization Protein Transport Glycosylation
Pathways		COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Diseases		None	Congenital disorders of glycosylation (CDG) type II
GWAS		Brain morphology (MOSTest) ( 32665545 ) Hippocampal volume in Alzheimer's disease dementia ( 29274321 ) Liver enzyme levels (alkaline phosphatase) ( 33972514 ) Malaria ( 31844061 ) Menarche (age at onset) ( 25231870 ) Weight ( 28552196 )	No GWAS studies recorded
Novel Interactors		1 novel interactors: PLA2G15	1 novel interactors: NHERF1
Interacting Genes		20 interacting genes: ANKRD11 APC BEX2 COG1 COG2 COG5 COG7 CTNNA3 DSCAM FAM110A FARSA ITSN1 MTNR1B NRIP1 PSMA1 RSPH1 SEPTIN2 SORBS3 TTC3 TXNDC9	5 interacting genes: COG3 COG4 DSCAM MTNR1A UBE2I
Entrez ID		25839	9382
HPRD ID		08444	07371
Ensembl ID		ENSG00000103051	ENSG00000166685
Uniprot IDs		A0A0A0MS45 A0A6I8PIQ6 J3KNI1 Q8N8L9 Q9H9E3	Q8WTW3
PDB IDs		3HR0	Not available
GO Terms Enriched among Interactors		Golgi Transport Complex Retrograde Transport, Vesicle Recycling Within Golgi Intra-Golgi Vesicle-mediated Transport Trans-Golgi Network Membrane Golgi Organization Glycosylation Golgi Vesicle Transport	Golgi Transport Complex Retrograde Transport, Vesicle Recycling Within Golgi Intra-Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding SUMO Conjugating Enzyme Activity Type 2 Metabotropic Glutamate Receptor Binding Regulation Of Renal Phosphate Excretion Dopamine Receptor Binding Renal Phosphate Ion Absorption Golgi Organization Trans-Golgi Network Membrane RING-like Zinc Finger Domain Binding Type 3 Metabotropic Glutamate Receptor Binding Melatonin Receptor Activity SUMO Ligase Complex HLH Domain Binding Glycosylation Positive Regulation Of Axon Extension Involved In Axon Guidance Small Protein Activating Enzyme Binding Maintenance Of Epithelial Cell Apical/basal Polarity Bile Acid Secretion Microvillus Assembly Channel Activator Activity Gamma-aminobutyric Acid Transmembrane Transporter Activity Beta-2 Adrenergic Receptor Binding Chloride Channel Regulator Activity Gamma-aminobutyric Acid Import Growth Factor Receptor Binding Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Microvillus Organization Establishment Of Golgi Localization Phospholipase C-activating Dopamine Receptor Signaling Pathway Netrin-activated Signaling Pathway Intracellular Phosphate Ion Homeostasis Mitotic Nuclear Membrane Reassembly Glutathione Transport Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Golgi Vesicle Transport Regulation Of Axon Extension Involved In Axon Guidance Dendrite Self-avoidance Camera-type Eye Photoreceptor Cell Differentiation Regulation Of Locomotion Dendritic Spine Development Hormone Binding Transferase Complex Intracellular Transport Negative Regulation Of Sodium Ion Transport Gamma-aminobutyric Acid Transport