HYPK and NAA15

Number of citations of the paper that reports this interaction (PubMedID 29754825)
64

Data Source:
BioGRID (x-ray crystallography, pull down, cross-linking study)

		HYPK	NAA15
Description		huntingtin interacting protein K	N-alpha-acetyltransferase 15, NatA auxiliary subunit
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Protein-containing Complex	Nucleus Transcription Regulator Complex Cytoplasm Cytosol Membrane Nuclear Body NatA Complex
	Molecular Function	Protein Binding Protein Folding Chaperone	RNA Binding Protein Binding Acetyltransferase Activator Activity Acetyltransferase Activity Ribosome Binding
	Biological Process	Protein Folding Negative Regulation Of Apoptotic Process Protein Stabilization	Angiogenesis N-terminal Protein Amino Acid Acetylation Cell Differentiation Negative Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Protein Stabilization
Pathways
Drugs
Diseases
GWAS
Interacting Genes		31 interacting genes: BOLL C2orf68 CSNK2B CYSRT1 HNRNPF HTT KRTAP12-2 KRTAP19-5 KRTAP3-2 KRTAP3-3 KRTAP8-1 MAGEA1 MAP1LC3B MDFI NAA10 NAA15 NEDD8 PCBP1 PHC3 PRR20A PRR20B PRR20C PRR20D PRR20E RBFOX1 RHOXF2 SP4 TENT5A THAP1 TXLNA VENTX	10 interacting genes: CDC42 CEBPA HYPK NAA10 NAA11 NAA50 RNF10 RPL26 XRCC5 XRCC6
Entrez ID		25764	80155
HPRD ID		13724	10471
Ensembl ID		ENSG00000242028	ENSG00000164134
Uniprot IDs		Q9NX55	A0A0B4J1W3 B2RBE5 Q9BXJ9
PDB IDs		6C95 6PW9 9F1D	6C95 6C9M 6PPL 6PW9 9F1B 9F1C 9F1D 9FPZ 9FQ0
Enriched GO Terms of Interacting Partners?		Intermediate Filament NatA Complex N-terminal Protein Amino Acid Acetylation	Protein-N-terminal Amino-acid Acetyltransferase Activity NatA Complex N-terminal Protein Amino Acid Acetylation Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Cellular Response To Gamma Radiation DNA End Binding Ku70:Ku80 Complex Protein N-terminal-serine Acetyltransferase Activity Protein Acetylation Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups DNA-dependent Protein Kinase Complex Response To Gamma Radiation Nucleolus DNA-dependent Protein Kinase-DNA Ligase 4 Complex 5'-deoxyribose-5-phosphate Lyase Activity Cellular Response To Ionizing Radiation Nonhomologous End Joining Complex Transcription Cis-regulatory Region Binding Nuclear Telomere Cap Complex Double-stranded Telomeric DNA Binding Chromosome Organization Protein-containing Complex Response To Ionizing Radiation Acyltransferase Activity Hematopoietic Stem Cell Proliferation Telomeric DNA Binding Cellular Response To Radiation ATP-dependent Activity, Acting On DNA DNA Helicase Activity Protein-DNA Complex Macrophage Differentiation Double-strand Break Repair Via Nonhomologous End Joining RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Translation Involved In Cellular Response To UV Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Damaged DNA Binding Protein Maturation Positive Regulation Of Protein Metabolic Process Stem Cell Proliferation Regulation Of Cell Development Protein-containing Complex Binding Macromolecule Metabolic Process GBD Domain Binding Storage Vacuole Response To Vitamin B2 C/EBP Complex Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Organelle Organization Regulation Of Cell Population Proliferation
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