FRMD3 and TMEM97

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FRMD3	TMEM97
Description		FERM domain containing 3	transmembrane protein 97
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Membrane	Nucleus Lysosome Endoplasmic Reticulum Rough Endoplasmic Reticulum Plasma Membrane Membrane Rough Endoplasmic Reticulum Membrane Nuclear Membrane
	Molecular Function	Protein Binding Cytoskeletal Protein Binding	Protein Binding Oxysterol Binding Cholesterol Binding
	Biological Process	Actomyosin Structure Organization	Regulation Of Cell Growth Regulation Of Intracellular Lipid Transport Regulation Of Intracellular Cholesterol Transport Cholesterol Homeostasis Positive Regulation Of Wound Healing Positive Regulation Of Lipoprotein Transport
Pathways
Drugs
Diseases
GWAS		Blood pressure traits (multi-trait analysis) ( 28498854) Hypertension ( 28498854) Insulin sensitivity index ( 24699409) Lewy body disease ( 25188341) Loneliness (multivariate analysis) ( 27629369) Metabolite levels ( 23823483)	Advanced age-related macular degeneration ( 26691988) Osteoprotegerin levels ( 25080503)
Interacting Genes		12 interacting genes: CMTM7 CYB5B JAGN1 NRM PLPP4 SERP1 SERP2 SLC35A4 TMEM201 TMEM218 TMEM97 ZFPL1	66 interacting genes: APP AQP12B AQP2 AQP6 ARL13B ASZ1 ATP6AP2 BCL2L13 BIK CD53 CD74 CD79A CGRRF1 CLDN7 CLSTN3 CPLX4 EBP ERGIC3 FAM209A FFAR2 FKBP7 FRMD3 FXYD3 GJA8 GJB3 GJB5 GPR152 GPR37L1 GPX8 HSD17B13 IFNGR2 KIR2DL3 LEUTX LHFPL5 LIME1 LRRC59 MFF MRM1 MTIF3 MUC1 NDUFAF1 NDUFAF2 NEMP1 PDCD1LG2 PDZK1IP1 PLP1 PSCA REEP1 RHCG RNF170 SAR1A SGPL1 SLC10A1 SLC14A1 SLC14A2 SLC18A1 SLC35H1 SPINT1 SSMEM1 TMEM106C TMEM14B TMEM45B TMEM52B TMEM79 TMX2 VSIR
Entrez ID		257019	27346
HPRD ID		07402	14343
Ensembl ID		ENSG00000172159	ENSG00000109084
Uniprot IDs		A2A2Y4	Q5BJF2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Nuclear Membrane Nuclear Inner Membrane Protein Localization To Extracellular Region Hormone Secretion Insulin Secretion Peptide Hormone Secretion Response To Unfolded Protein Response To Endoplasmic Reticulum Stress Hormone Transport Endoplasmic Reticulum Unfolded Protein Response Establishment Of Protein Localization To Extracellular Region Protein Secretion Regulation Of Protein Transport Peptide Transport Peptide Secretion Positive Regulation Of Lipoprotein Transport Nitric-oxide Synthase Complex Nitrite Reductase (NO-forming) Activity Granulocyte Colony-stimulating Factor Signaling Pathway B-1a B Cell Differentiation B-1 B Cell Differentiation Pyrimidine Nucleotide-sugar Transmembrane Transporter Activity Diacylglycerol Diphosphate Phosphatase Activity Nuclear Migration Along Microtubule	Membrane Water Transport One-carbon Compound Transport Fluid Transport Protein Binding Water Channel Activity Endoplasmic Reticulum Membrane Connexin Complex Endoplasmic Reticulum Gap Junction Channel Activity Plasma Membrane B Cell Receptor Complex Water Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Mitochondrial Membrane Gap Junction Urea Transmembrane Transporter Activity Transmembrane Transport
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