KRTAP15-1 and NOXA1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP15-1	NOXA1
Description		keratin associated protein 15-1	NADPH oxidase activator 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Cytoplasm Cytosol Plasma Membrane Membrane NADPH Oxidase Complex
	Molecular Function	Protein Binding	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Small GTPase Binding Identical Protein Binding
	Biological Process		Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Superoxide Anion Generation Regulation Of Respiratory Burst
Pathways		Keratinization	RHO GTPases Activate NADPH Oxidases RAC1 GTPase cycle RAC3 GTPase cycle WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS			Response to fenofibrate (total cholesterol levels) ( 27002377)
Interacting Genes		71 interacting genes: ACY3 ANKHD1 ARID5A ASB13 ATN1 C10orf55 CAMK2A CCDC24 CERCAM CYSRT1 DTX2 FCHO1 FOXD2 GEMIN4 GRN HOXA1 HR INCA1 INTS11 ITGB4 KPRP KRTAP10-8 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP13-2 KRTAP19-1 KRTAP19-5 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP5-11 KRTAP5-3 KRTAP6-2 KRTAP9-2 MGAT5B NEU4 NHLRC4 NOXA1 PATZ1 PEF1 PITX2 PLSCR3 POU1F1 POU2AF1 PRR13 PSMB1 RBPMS RHOXF2 RIN1 RNF208 SLC15A2 SMUG1 SOX14 SPAG8 TEKT3 TEKT5 TFAP2D TLE3 TOLLIP UBAP2 UFSP1 VAC14 VGLL3 VPS37C VWCE WDR25 YPEL3 ZBTB32 ZIC1	57 interacting genes: ACTMAP ANKRD55 CACNA1A CEP70 CFP CRYBA1 CTDSP1 CYSRT1 DCLRE1B DDAH2 DUSP4 EP300 FAT1 GATAD2B IL16 KCTD15 KRTAP13-1 KRTAP15-1 KRTAP19-4 KRTAP19-7 KRTAP8-1 LASP1 LMO2 MAPK1 MAPK11 METTL27 MORN3 MYLIP NAA10 NADSYN1 NCF1 NDUFAB1 NOX1 NOXO1 PFDN5 PLA2G10 PRKACA PRKCA PRKCG QARS1 RAC1 RAC2 REL RIMBP3 RIMBP3C SMUG1 SPMIP6 TCF19 TCF4 TGS1 TRAF2 TRIM23 UBAP2 WDR83 ZC2HC1C ZNF474 ZNF620
Entrez ID		254950	10811
HPRD ID		11204	17644
Ensembl ID		ENSG00000186970	ENSG00000188747
Uniprot IDs		Q3LI76	Q86UR1
PDB IDs			7CFZ
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Protein Binding Axonemal A Tubule Inner Sheath	NADPH Oxidase Complex Superoxide Anion Generation Superoxide Metabolic Process Regulation Of Respiratory Burst Respiratory Burst Regulation Of Hydrogen Peroxide Metabolic Process Reactive Oxygen Species Metabolic Process Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Manchette Benzodiazepine Receptor Binding Erythrocyte Enucleation Protein Binding Intermediate Filament Signal Transduction Involved In Regulation Of Gene Expression Regulation Of Cytokine Production Superoxide-generating NADPH Oxidase Activator Activity Intracellular Signaling Cassette Internal Protein Amino Acid Acetylation Negative Regulation Of Glial Cell Apoptotic Process Thioesterase Binding
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