TSGA10IP and LIPE

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TSGA10IP	LIPE
Description		testis specific 10 interacting protein	lipase E, hormone sensitive type
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Photoreceptor Connecting Cilium	Cytoplasm Lipid Droplet Cytosol Plasma Membrane Caveola Membrane
	Molecular Function	Protein Binding	Sterol Ester Esterase Activity Triacylglycerol Lipase Activity Protein Binding Lipase Activity Hydrolase Activity Monoacylglycerol Lipase Activity All-trans-retinyl-palmitate Hydrolase, All-trans-retinol Forming Activity Retinyl-palmitate Esterase Activity Diacylglycerol Lipase Activity
	Biological Process	Cilium Organization	Protein Phosphorylation Lipid Metabolic Process Steroid Metabolic Process Cholesterol Metabolic Process Lipid Catabolic Process Triglyceride Catabolic Process Retinol Metabolic Process Diacylglycerol Catabolic Process Ether Lipid Metabolic Process
Pathways			Triglyceride catabolism MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Severe influenza A (H1N1) infection ( 26379185) Urate levels ( 31578528)
Interacting Genes		112 interacting genes: AIRIM AKAP8L AMOTL2 AP1B1 ARHGEF9 BICD2 BICDL2 BIRC7 BRCA1 CALCOCO2 CARD9 CAVIN1 CBY2 CCDC102B CCDC120 CCDC125 CCDC13 CCDC136 CCDC57 CCDC88B CDKN2D CDR2 CDR2L CEP63 CEP70 CIB1 CRACR2B CTAG1A CTAG1B CYSRT1 DMAP1 DRC4 DYDC1 EFHC1 FCHSD2 FHL3 FRS3 FSD2 GOLGA2 GOLGA6A GOLGA6L9 GPRASP3 GRIPAP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKZF3 JAKMIP1 KANK2 KHDRBS3 KIFC3 KRT24 KRT36 KRT40 KRT86 KRTAP12-2 KRTAP6-2 LCA5L LDOC1 LIPE LMNB2 LMO2 LZTS1 MAGED1 MBD3L1 MDFI MEIS3 MEOX2 MIPOL1 MIS18A MKRN3 MSS51 MTUS2 NAB2 NCOA5 NUTM1 PARVG PDLIM7 PICK1 PRDM6 PRKAR1B PSTPIP1 RASGEF1B RBM4B RBPMS ROPN1 RORB RUNDC3A SAAL1 SORBS3 SPG21 SSX2IP STX11 STX1A TBC1D1 TEKT1 TFIP11 TLE5 TRAF2 TRAF4 TRIM27 TRIM5 TRIM50 TRIP6 TSC1 TTC23 TTC23L UHMK1 WWOX YES1 ZRANB1	11 interacting genes: FABP4 KATNA1 MAPK1 MAPK3 MTNR1A NSFL1C PLIN1 PLIN5 PRKACA STAR TSGA10IP
Entrez ID		254187	3991
HPRD ID		08147	01062
Ensembl ID		ENSG00000175513	ENSG00000079435
Uniprot IDs		Q3SY00	A8K8W7 Q05469
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Cytoskeleton Microtubule-based Process Cytoskeleton Organization Cytoplasm Centrosome Organelle Organization Intermediate Filament Golgi To Secretory Granule Transport Microtubule Cytoskeleton Organization Microtubule Organizing Center Organization Microtubule-based Movement Cytoskeleton-dependent Intracellular Transport	Positive Regulation Of Small Molecule Metabolic Process Positive Regulation Of Steroid Metabolic Process Positive Regulation Of Lipid Metabolic Process Positive Regulation Of Lipid Biosynthetic Process Positive Regulation Of Steroid Biosynthetic Process Regulation Of Golgi Inheritance Interleukin-34-mediated Signaling Pathway Caveolin-mediated Endocytosis Positive Regulation Of Macrophage Proliferation Regulation Of Lipid Biosynthetic Process Cardiac Neural Crest Cell Development Involved In Heart Development Trachea Formation Outer Ear Morphogenesis ERBB3 Signaling Pathway ERBB2-ERBB3 Signaling Pathway Regulation Of Steroid Biosynthetic Process Bergmann Glial Cell Differentiation Lipid Droplet Cellular Response To Tumor Necrosis Factor Cellular Response To Cold Regulation Of Lipid Metabolic Process Regulation Of Small Molecule Metabolic Process Regulation Of Steroid Metabolic Process Lipid Binding MAP Kinase Activity Regulation Of Golgi Organization Pseudopodium Response To Tumor Necrosis Factor Regulation Of Early Endosome To Late Endosome Transport Schwann Cell Development Positive Regulation Of Macrophage Chemotaxis Positive Regulation Of Neuroinflammatory Response Animal Organ Formation Positive Regulation Of Cholesterol Biosynthetic Process Face Development Stress-activated MAPK Cascade ERBB2 Signaling Pathway Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Macrophage Migration Neural Crest Cell Development Lung Morphogenesis Positive Regulation Of Inflammatory Response Positive Regulation Of Cholesterol Metabolic Process Regulation Of Macrophage Chemotaxis Thyroid Gland Development Regulation Of Cholesterol Biosynthetic Process Astrocyte Differentiation Insulin-like Growth Factor Receptor Signaling Pathway Stem Cell Development Regulation Of Stress-activated MAPK Cascade
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