TSGA10IP and ARHGEF9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TSGA10IP	ARHGEF9
Description		testis specific 10 interacting protein	Cdc42 guanine nucleotide exchange factor 9
Image		No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Photoreceptor Connecting Cilium	Cytoplasm Cytosol Postsynaptic Density Synapse GABA-ergic Synapse Postsynaptic Specialization
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Cilium Organization	Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Postsynaptic Specialization Assembly
Pathways			NRAGE signals death through JNK G alpha (12/13) signalling events CDC42 GTPase cycle RHOQ GTPase cycle GABA receptor activation GABA receptor activation
Drugs
Diseases			Hyperekplexia Early infantile epileptic encephalopathy; Ohtahara syndrome
GWAS		Acne (severe) ( 24927181) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Severe influenza A (H1N1) infection ( 26379185) Urate levels ( 31578528)	Male-pattern baldness ( 28196072)
Interacting Genes		112 interacting genes: AIRIM AKAP8L AMOTL2 AP1B1 ARHGEF9 BICD2 BICDL2 BIRC7 BRCA1 CALCOCO2 CARD9 CAVIN1 CBY2 CCDC102B CCDC120 CCDC125 CCDC13 CCDC136 CCDC57 CCDC88B CDKN2D CDR2 CDR2L CEP63 CEP70 CIB1 CRACR2B CTAG1A CTAG1B CYSRT1 DMAP1 DRC4 DYDC1 EFHC1 FCHSD2 FHL3 FRS3 FSD2 GOLGA2 GOLGA6A GOLGA6L9 GPRASP3 GRIPAP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKZF3 JAKMIP1 KANK2 KHDRBS3 KIFC3 KRT24 KRT36 KRT40 KRT86 KRTAP12-2 KRTAP6-2 LCA5L LDOC1 LIPE LMNB2 LMO2 LZTS1 MAGED1 MBD3L1 MDFI MEIS3 MEOX2 MIPOL1 MIS18A MKRN3 MSS51 MTUS2 NAB2 NCOA5 NUTM1 PARVG PDLIM7 PICK1 PRDM6 PRKAR1B PSTPIP1 RASGEF1B RBM4B RBPMS ROPN1 RORB RUNDC3A SAAL1 SORBS3 SPG21 SSX2IP STX11 STX1A TBC1D1 TEKT1 TFIP11 TLE5 TRAF2 TRAF4 TRIM27 TRIM5 TRIM50 TRIP6 TSC1 TTC23 TTC23L UHMK1 WWOX YES1 ZRANB1	12 interacting genes: BCL6 CDC42 CFTR FAM90A1 GPHN IHO1 KHDRBS1 PLEKHA5 SMURF1 TBC1D22B TFIP11 TSGA10IP
Entrez ID		254187	23229
HPRD ID		08147	02337
Ensembl ID		ENSG00000175513	ENSG00000131089
Uniprot IDs		Q3SY00	A0A1B0GWI5 A0A5F9ZHY9 A0A5F9ZI31 B1AMR3 O43307
PDB IDs			2YSQ
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Cytoskeleton Microtubule-based Process Cytoskeleton Organization Cytoplasm Centrosome Organelle Organization Intermediate Filament Golgi To Secretory Granule Transport Microtubule Cytoskeleton Organization Microtubule Organizing Center Organization Microtubule-based Movement Cytoskeleton-dependent Intracellular Transport
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