STXBP4 and STX4

Number of citations of the paper that reports this interaction (PubMedID 12855681)
0

Data Source:
HPRD (in vitro, in vivo)

		STXBP4	STX4
Description		syntaxin binding protein 4	syntaxin 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoplasmic Vesicle Phagocytic Vesicle Extracellular Exosome	Storage Vacuole Extracellular Space Cytoplasm Endosome Vacuole Trans-Golgi Network Cytosol Plasma Membrane Cell Surface Endomembrane System Membrane Basolateral Plasma Membrane Lamellipodium Phagocytic Vesicle Membrane SNARE Complex Stereocilium Neuron Projection Membrane Myelin Sheath Adaxonal Region Somatodendritic Compartment Specific Granule Cell Projection Neuron Projection Dendritic Spine Lateral Loop Synapse Phagocytic Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome Schaffer Collateral - CA1 Synapse Postsynapse Glutamatergic Synapse
	Molecular Function	Protein Binding Syntaxin Binding	SNARE Binding SNAP Receptor Activity Protein Binding Sphingomyelin Phosphodiesterase Activator Activity
	Biological Process	Protein Targeting Response To Stress DNA Damage Response Insulin Receptor Signaling Pathway Regulation Of D-glucose Transmembrane Transport Positive Regulation Of Keratinocyte Proliferation Protein Stabilization Regulation Of Transport Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cellular Response To Type II Interferon Positive Regulation Of Cell Cycle G1/S Phase Transition	Positive Regulation Of Immunoglobulin Production Neurotransmitter Transport Intracellular Protein Transport Exocytosis Vesicle Fusion Sensory Perception Of Sound Positive Regulation Of Cell Population Proliferation Vesicle-mediated Transport Regulation Of Exocytosis Positive Regulation Of Cell Migration Protein Localization To Cell Surface Cellular Response To Oxidative Stress SNARE Complex Assembly Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Catalytic Activity Positive Regulation Of Eosinophil Degranulation Positive Regulation Of Cell Adhesion Vesicle Docking Organelle Fusion Positive Regulation Of Chemotaxis Long-term Synaptic Potentiation Membrane Organization Cellular Response To Type II Interferon Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Protein Localization To Plasma Membrane Cornified Envelope Assembly Positive Regulation Of Protein Localization To Cell Surface
Pathways			Disinhibition of SNARE formation ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Other interleukin signaling
Drugs
Diseases
GWAS		Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Intrinsic epigenetic age acceleration ( 29374233) Menarche (age at onset) ( 25231870) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Night sleep phenotypes ( 27126917) Plateletcrit ( 32888494) Systolic blood pressure ( 34074324) Zinc levels ( 26025379)	Response to metformin (IC50) ( 28173075) Triglyceride levels ( 32203549)
Interacting Genes		5 interacting genes: ATN1 ENKD1 KLHL42 STX4 TRIM54	65 interacting genes: ABI2 ACTB ANKRD46 BET1 CYBRD1 DLG1 DNAJC5 FAXDC2 GIMAP5 GOSR2 GPR152 ITSN2 LLGL1 LMNA NAPA NAPB NSF PLP1 PSMA3 RAB11A RAB4A RAB5A RNF4 SCRIB SEC22A SEC22B SEPTIN5 SERP1 SGPL1 SH3GLB2 SNAP23 SNAP25 SNAP47 STX10 STX11 STX16 STX1A STX1B STX2 STX3 STX5 STXBP3 STXBP4 STXBP5 STXBP6 SYT1 SYT4 SYT7 TCEANC TMEM203 TRAF3IP3 TXLNA TXLNB TXLNG USE1 VAMP1 VAMP2 VAMP3 VAMP4 VAMP7 VAMP8 VAPB VMA12 VTI1B ZFPL1
Entrez ID		252983	6810
HPRD ID		18127	01722
Ensembl ID		ENSG00000166263	ENSG00000103496
Uniprot IDs		B5MCT9 Q6ZWJ1	B7Z425 Q12846
PDB IDs		2YSG
Enriched GO Terms of Interacting Partners?		9+0 Non-motile Cilium Microtubule Associated Complex Microtubule Sphingomyelin Phosphodiesterase Activator Activity Myosin V Complex Positive Regulation Of Eosinophil Degranulation Storage Vacuole Cytoskeleton Neuron Projection Membrane Lateral Loop	SNAP Receptor Activity SNARE Complex Membrane Fusion Syntaxin Binding Vesicle Fusion Organelle Membrane Fusion Organelle Fusion Vesicle-mediated Transport Membrane Organization SNARE Binding Vesicle Organization Exocytosis Organelle Localization By Membrane Tethering Establishment Of Localization In Cell Membrane Docking Secretion By Cell Vesicle Docking Protein Transport Secretion Establishment Of Protein Localization Vesicle-mediated Transport In Synapse Golgi Vesicle Transport Cellular Localization Intracellular Protein Localization Intracellular Transport Organelle Localization Regulation Of Vesicle-mediated Transport Endomembrane System Calcium-ion Regulated Exocytosis SNARE Complex Assembly Membrane Regulated Exocytosis Regulation Of Exocytosis Syntaxin-1 Binding Synaptic Vesicle Exocytosis Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Intracellular Protein Transport Vesicle Fusion To Plasma Membrane Regulation Of Secretion By Cell Synaptic Vesicle Membrane Regulation Of Secretion Synaptic Vesicle Membrane Organization Signal Release Regulation Of Transport Regulation Of Regulated Secretory Pathway Synaptic Vesicle Calcium Ion-regulated Exocytosis Of Neurotransmitter Vesicle Docking Involved In Exocytosis Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Post-Golgi Vesicle-mediated Transport
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