ARHGAP8 and CYGB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARHGAP8	CYGB
Description		Rho GTPase activating protein 8	cytoglobin
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Cytoplasm Cytosol Nuclear Speck Neuron Projection Neuronal Cell Body
	Molecular Function	GTPase Activator Activity Protein Binding	Catalase Activity Peroxidase Activity Superoxide Dismutase Activity Oxygen Carrier Activity Iron Ion Binding Protein Binding Antioxidant Activity Oxidoreductase Activity Oxygen Binding Heme Binding Metal Ion Binding Fatty Acid Peroxidase Activity Carbon Monoxide Binding Nitrite Reductase Activity Nitric Oxide Dioxygenase Activity, Heme Protein As Donor
	Biological Process	Signal Transduction Small GTPase-mediated Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Endocytic Recycling	Response To Hypoxia Response To Oxidative Stress Negative Regulation Of Fibroblast Migration Oxygen Transport Fatty Acid Oxidation Removal Of Superoxide Radicals Negative Regulation Of Collagen Biosynthetic Process Nitric Oxide Metabolic Process Nitric Oxide Catabolic Process Negative Regulation Of Hepatic Stellate Cell Activation
Pathways		RHOA GTPase cycle	eNOS activation Intracellular oxygen transport
Drugs
Diseases
GWAS		Binge eating behaviour in bipolar disorder ( 29391396) Body mass index ( 28552196) Electroencephalographic traits in alcoholism ( 22554406) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600) Weight ( 28552196)
Interacting Genes		7 interacting genes: BNIP2 CFTR CTTN CYGB RHOA SH3GL1 ZMYND12	6 interacting genes: ARHGAP8 ATP13A2 DDI1 LRATD1 MZT1 PRR5-ARHGAP8
Entrez ID		23779	114757
HPRD ID		06448	06479
Ensembl ID		ENSG00000241484	ENSG00000161544
Uniprot IDs		P85298 Q6PJW1	Q8WWM9
PDB IDs			1UMO 1URV 1URY 1UT0 1UX9 1V5H 2DC3 3AG0 4B3W
Enriched GO Terms of Interacting Partners?		Regulation Of Smooth Muscle Contraction Aortic Valve Formation Angiotensin-mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Neuron Differentiation Odontogenesis Positive Regulation Of Vascular Associated Smooth Muscle Contraction Endothelial Tube Lumen Extension Mitotic Cleavage Furrow Formation Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Muscle Contraction Skeletal Muscle Satellite Cell Migration Cell Projection Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Podosome Negative Regulation Of Hepatic Stellate Cell Activation Nitric Oxide Catabolic Process Fatty Acid Peroxidase Activity Nitric Oxide Dioxygenase Activity, Heme Protein As Donor Beta Selection Glutamatergic Synapse Positive Regulation Of Monoatomic Anion Transport Catalase Activity Carbon Monoxide Binding Bone Trabecula Morphogenesis Dendritic Spine Positive Regulation Of Enamel Mineralization Superoxide Dismutase Activity Nitrite Reductase Activity Apolipoprotein A-I-mediated Signaling Pathway Positive Regulation Of Cytoskeleton Organization Lamellipodium Endosome Cleavage Furrow Formation Regulation Of Neuron Differentiation Positive Regulation Of Supramolecular Fiber Organization Cell Cortex Regulation Of Systemic Arterial Blood Pressure By Endothelin Cell Junction Regulation Of Muscle Contraction Positive Regulation Of Protein-containing Complex Assembly Roundabout Signaling Pathway Forebrain Radial Glial Cell Differentiation Regulation Of Modification Of Postsynaptic Actin Cytoskeleton Early Endosome Membrane Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport	WW Domain Binding Spermine Transmembrane Transport ABC-type Polyamine Transporter Activity Microtubule Nucleation By Interphase Microtubule Organizing Center
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?