PISD and DAGLB

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PISD	DAGLB
Gene Name		phosphatidylserine decarboxylase	diacylglycerol lipase, beta
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane
	Molecular Function	Phosphatidylserine Decarboxylase Activity	Lipase Activity Metal Ion Binding
	Biological Process	Phospholipid Metabolic Process Phosphatidylethanolamine Biosynthetic Process Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process	Neuroblast Proliferation Blood Coagulation Lipid Catabolic Process Arachidonic Acid Metabolic Process Platelet Activation Neurotransmitter Biosynthetic Process
Pathways		Metabolism of lipids and lipoproteins Synthesis of PE Phospholipid metabolism Glycerophospholipid biosynthesis	G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK Arachidonate production from DAG Platelet activation, signaling and aggregation Effects of PIP2 hydrolysis
Drugs		Phosphatidylserine
Diseases
GWAS		Intelligence ( 22449649) Paclitaxel-induced neuropathy ( 23776197)
Protein-Protein Interactions		3 interactors: BRCA1 DAGLB DHX29	1 interactors: PISD
Entrez ID		23761	221955
HPRD ID		17854	17324
Ensembl ID		ENSG00000241878	ENSG00000164535
Uniprot IDs		Q9UG56	Q8NCG7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Fatty Acid Metabolic Process Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Dosage Compensation By Inactivation Of X Chromosome Protein K6-linked Ubiquitination Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Regulation Of Histone H4 Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Fatty Acid Biosynthetic Process DNA Damage Response, Signal Transduction Resulting In Transcription Monocarboxylic Acid Metabolic Process Negative Regulation Of Histone Methylation Neurotransmitter Biosynthetic Process Negative Regulation Of Centrosome Duplication Regulation Of DNA Methylation Negative Regulation Of Histone Acetylation Positive Regulation Of Histone Acetylation Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Histone H3-K4 Methylation Negative Regulation Of Protein Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Postreplication Repair Regulation Of Transcription From RNA Polymerase III Promoter Negative Regulation Of Fatty Acid Metabolic Process Regulation Of Gene Expression By Genetic Imprinting Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Neurotransmitter Metabolic Process Genetic Imprinting Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Vascular Endothelial Growth Factor Production G2 DNA Damage Checkpoint Positive Regulation Of Histone Methylation Positive Regulation Of DNA Repair Cellular Lipid Metabolic Process Androgen Receptor Signaling Pathway Regulation Of Centrosome Duplication Protein Autoubiquitination Carboxylic Acid Metabolic Process Regulation Of Histone Acetylation	Phosphatidylethanolamine Biosynthetic Process Glycerophospholipid Biosynthetic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Phospholipid Metabolic Process Glycerolipid Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?