PISD

Description		phosphatidylserine decarboxylase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Golgi Apparatus Lipid Droplet Cytosol Membrane
	Molecular Function	Phosphatidylserine Decarboxylase Activity Protein Binding Lyase Activity Carboxy-lyase Activity
	Biological Process	Lipid Metabolic Process Phosphatidylethanolamine Biosynthetic Process Phospholipid Biosynthetic Process Regulation Of Mitochondrion Organization Protein Autoprocessing Mitochondrial Protein Catabolic Process Lipid Droplet Formation
Pathways		Synthesis of PE
Drugs		Phosphatidyl serine
Diseases
GWAS		Age-related hearing impairment ( 24939585) Fish- and plant-related diet ( 32066663) Intelligence ( 22449649) Oily fish consumption ( 32066663) Paclitaxel-induced neuropathy ( 23776197) Pork consumption ( 32066663)
Interacting Genes		6 interacting genes: BRCA1 CFTR CIDEB DAGLB DHX29 UBC
Entrez ID		23761
HPRD ID		17854
Ensembl ID		ENSG00000241878
Uniprot IDs		Q9UG56
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Lipid Metabolic Process Small Molecule Biosynthetic Process Histone H2AK127 Ubiquitin Ligase Activity Fatty Acid Biosynthetic Process Histone H2AK129 Ubiquitin Ligase Activity Lipid Biosynthetic Process BRCA1-BARD1 Complex Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Regulation Of Triglyceride Metabolic Process Positive Regulation Of Monoatomic Anion Transport Cannabinoid Biosynthetic Process BRCA1-B Complex Positive Regulation Of Enamel Mineralization Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Centriole Replication BRCA1-A Complex Nuclear Ubiquitin Ligase Complex Cellular Response To Indole-3-methanol BRCA1-C Complex Ubiquitin-modified Histone Reader Activity Response To Indole-3-methanol Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Lipid Droplet Fusion Formation Of Translation Preinitiation Complex Positive Regulation Of Triglyceride Catabolic Process Diacylglycerol Catabolic Process Monoacylglycerol Biosynthetic Process Negative Regulation Of Centrosome Duplication Lipid Metabolic Process XY Body Fatty Acid Metabolic Process Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Lateral Element Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Gamma-tubulin Ring Complex Apoptotic Signaling Pathway Ubiquitin Protein Ligase Binding DNA Strand Resection Involved In Replication Fork Processing Response To Alcohol
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