DAGLB

Description		diacylglycerol lipase beta
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosomal Membrane Plasma Membrane Membrane
	Molecular Function	Triacylglycerol Lipase Activity Protein Binding Lipase Activity Hydrolase Activity Metal Ion Binding Monoacylglycerol Lipase Activity
	Biological Process	Prostaglandin Biosynthetic Process Lipid Metabolic Process Monoacylglycerol Biosynthetic Process Icosanoid Metabolic Process Neuroblast Proliferation Positive Regulation Of Triglyceride Catabolic Process Lipid Catabolic Process Arachidonate Metabolic Process Neurogenesis Diacylglycerol Catabolic Process Regulation Of Inflammatory Response Cannabinoid Biosynthetic Process
Pathways		Arachidonate production from DAG
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Body mass index ( 26426971) Coronary artery disease ( 29212778) HDL cholesterol ( 24097068 30275531) HDL cholesterol levels ( 32203549 28334899) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) High density lipoprotein cholesterol levels ( 33339817) Inflammatory bowel disease ( 28067908) Lymphocyte percentage of white cells ( 27863252) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 27863252) Red cell distribution width ( 32888494) Ulcerative colitis ( 28067908) Waist-hip ratio and HDL-C (pairwise) ( 33619380) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		5 interacting genes: CLP1 KRTAP1-3 NBPF19 NOTCH2NLA PISD
Entrez ID		221955
HPRD ID		17324
Ensembl ID		ENSG00000164535
Uniprot IDs		Q8NCG7
PDB IDs
Enriched GO Terms of Interacting Partners?		ATP-dependent Polyribonucleotide 5'-hydroxyl-kinase Activity Polynucleotide 5'-hydroxyl-kinase Activity ATP-dependent Polynucleotide 5'-hydroxyl-kinase Activity Phosphatidylserine Decarboxylase Activity TRNA-intron Endonuclease Complex Global Gene Silencing By MRNA Cleavage ATP-dependent Polydeoxyribonucleotide 5'-hydroxyl-kinase Activity MRNA Cleavage Factor Complex Cerebellar Cortex Development RISC Complex Assembly Phosphatidylethanolamine Biosynthetic Process Mitochondrial Protein Catabolic Process TRNA Splicing, Via Endonucleolytic Cleavage And Ligation Lipid Droplet Formation Protein Autoprocessing Carboxy-lyase Activity Notch Binding
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