LEPROTL1 and PAQR8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LEPROTL1	PAQR8
Description		leptin receptor overlapping transcript like 1	progestin and adipoQ receptor family member 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Membrane	Golgi Apparatus Plasma Membrane Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Nuclear Steroid Receptor Activity Steroid Binding Protein Binding Lipid Binding
	Biological Process	Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Growth Hormone Receptor Signaling Pathway	Cell Differentiation Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Oogenesis Response To Steroid Hormone
Pathways
Drugs
Diseases
GWAS			Atopic march ( 26542096) Platelet count ( 27863252 32888494)
Interacting Genes		73 interacting genes: AGPAT4 ARL13B CD300C CD79A CISD2 CLDN7 CLEC2D CREB3L1 CYP4F2 EDA EHHADH ELOVL4 EMP1 FCER1G FFAR2 FMO1 GJA5 GJA8 GPR152 GPR42 GPX8 JPH1 KCNJ6 KLRG1 LMBR1 LMNA LNX1 LPAR3 LRRC4C MALL MSR1 NAT8 ORMDL3 PAQR8 PDZK1IP1 PEX16 PLP1 RBFA REEP4 REEP6 RNF5 RTP2 SCN3B SDCBP SFXN3 SLC16A2 SLC25A46 SLC30A4 SLC35H1 SLC71A2 SLC7A1 SMCO4 SPG21 SSMEM1 STING1 STX12 SYNDIG1 TGFA TMEM11 TMEM14B TMEM19 TMEM237 TMEM248 TMEM42 TMEM50A TMEM50B TMX2 TSNARE1 TSPAN2 TVP23A VAPA YIPF2 ZDHHC15	3 interacting genes: EHHADH LEPROTL1 MPP1
Entrez ID		23484	85315
HPRD ID		09551	07415
Ensembl ID		ENSG00000104660	ENSG00000170915
Uniprot IDs		O95214 Q6FHL7	B3KXW6 Q8TEZ7
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Protein Binding Plasma Membrane Endoplasmic Reticulum Cellular Localization Myelination Axon Ensheathment SA Node Cell Action Potential Transmembrane Transport	Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds Enoyl-CoA Hydratase Activity (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Delta(3)-delta(2)-enoyl-CoA Isomerase Activity 3-hydroxyacyl-CoA Dehydratase Activity GMP Kinase Activity Negative Regulation Of Growth Hormone Receptor Signaling Pathway Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase GDP Metabolic Process Regulation Of Growth Hormone Receptor Signaling Pathway Alpha-linolenic Acid Metabolic Process NAD+ Binding Cortical Cytoskeleton GMP Metabolic Process Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Long-chain Fatty Acid Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Stereocilium Regulation Of Neutrophil Chemotaxis Regulation Of Neutrophil Migration Endosome Transport Via Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Peroxisomal Matrix Fatty Acid Beta-oxidation Fatty Acid Derivative Biosynthetic Process Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Regulation Of Granulocyte Chemotaxis Multivesicular Body Sorting Pathway Fatty Acid Catabolic Process Fatty Acid Derivative Metabolic Process Fatty Acid Oxidation Nucleoside Monophosphate Metabolic Process Nucleoside Diphosphate Metabolic Process Ribonucleoside Diphosphate Metabolic Process Lipid Oxidation
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